1296201-71-2

Basic information

• Product Name: C₁₅H₂₁ClN₂OSi
• Synonyms: C₁₅H₂₁ClN₂OSi
• CAS NO: 1296201-71-2
• Molecular Weight: 308.883
• Mol File: 1296201-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₂₁ClN₂OSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₂₁ClN₂OSi(1296201-71-2)
• EPA Substance Registry System: C₁₅H₂₁ClN₂OSi(1296201-71-2)

Safety Data

• Hazardous Substances Data: 1296201-71-2(Hazardous Substances Data)

Upstream product

• 45644-21-1 6-chloropyridin-2-amine 
• 86847-84-9 2,2-Dimethyl-N-(6-chloro-2-pyridinyl)propanamide 
• 800402-05-5 N-(6-chloro-3-iodopyridin-2-yl)-tert-butylamide 
• 1066-54-2 trimethylsilylacetylene 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 915140-96-4 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid 

Relevant articles and documents

BICYCLIC HETEROARYLS AS KINASE INHIBITORS

The invention is directed to heteroaryl compounds useful as inhibitors of various kinase enzymes. In various embodiments, the invention provides a heteroaryl compound having inhibitory bioactivity with respect to a Rho kinase, an AKT kinase, a p70S6K kinase, a LIM kinase, an IKK kinase, a Flt kinase, an Aurora kinase, or a Src kinase, or any combination thereof. Compounds of the invention include bicyclic heteroaryl compounds of formula (I), which can contain a bridging nitrogen atom at a ring junction. The invention further provides methods of synthesis of compounds of the invention, pharmaceutical compositions, pharmaceutical combinations, and methods of treatment of malconditions using compounds of the invention.