13073-26-2Relevant articles and documents
Regioselective oxyiodination of aromatic compounds using potassium iodide and oxone
Narender,Srinivasu,Kulkarni,Raghavan
, p. 2319 - 2324 (2002)
A highly efficient, simple, mild and regioselective method for oxyiodination of aromatic compounds is reported. The electrophilic substitution of iodine generated in situ from KI as an iodine source and oxone as an oxidant for the first time.
Benzofuran-substituted urea derivatives as novel P2Y1 receptor antagonists
Thalji, Reema K.,Aiyar, Nambi,Davenport, Elizabeth A.,Erhardt, Joseph A.,Kallal, Lorena A.,Morrow, Dwight M.,Senadhi, Shobha,Burns-Kurtis, Cynthia L.,Marino Jr., Joseph P.
scheme or table, p. 4104 - 4107 (2010/08/07)
Benzofuran-substituted urea analogs have been identified as novel P2Y1 receptor antagonists. Structure-activity relationship studies around the urea and the benzofuran moieties resulted in compounds having improved potency. Several analogs were
Iodination of aromatic compounds using potassium iodide and hydrogen peroxide
Reddy, K. Suresh Kumar,Narender,Rohitha,Kulkarni
experimental part, p. 3894 - 3902 (2009/04/04)
A simple, efficient, regioselective, and ecofriendly method for oxyiodination of aromatic compounds is presented. In this method, the electrophilic substitutions of iodine generated in situ from KI as an iodine source and hydrogen peroxide as an oxygen source have been employed without any catalyst/mineral acid for the first time. Copyright Taylor & Francis Group, LLC.
Simple and regioselective oxyiodination of aromatic compounds with ammonium iodide and Oxone
Krishna Mohan,Narender,Kulkarni
, p. 8015 - 8018 (2007/10/03)
Oxyiodination of aromatic compounds using NH4I and Oxone gives high yields and selectivity. A simple method for the iodination of aromatic compounds using NH4I as the iodine source and Oxone as the oxidant is described.
Iodination of Thallium(I) salts of Phenols
Gambie, Richard C.,Larsen, David S.,Rutledge, Peter S.,Woodgate, Paul D.
, p. 767 - 769 (2007/10/03)
The iodination of thallium(I) salts of phenols is examined and the results are compared with those of the selective ortho-iodinating reagent thallium(I) acetate-iodine.
REACTION OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. VII. DIRECTION OF HYDROXYLATION OF 3-SUBSTITUTED (Cl, Br, I, NO2) NITROBENZENES WITH POTASSIUM HYDROXIDE
Malykhin, E. V.,Kolesnichenko, G. A.,Shteingarts, V. D.
, p. 720 - 726 (2007/10/02)
The reaction of 3-chloro-, 3-bromo-, and 3-iodonitrobenzenes with potassium hydroxide and oxygen in liquid ammonia (-33 deg C) leads to the formation of nitrohalogenophenols, corresponding to substitution of the hydrogen atom at the orto and para positions of the ring in relation to the nitro group by a hydroxy group.In the case of the last two substrates it also leads to the corresponding 2-halogeno-3',4'-dinitrodiphenylamines.In view of the fact that substitued diphenylamines are formed under the same conditions as a result of the reaction of 3-nitroaniline with 3-halogenonitrobenzenes it is suggested that 3-bromo- and 3-iodonitrobenzenes are partly converted into 3-nitroaniline through the intermediate formation of 3-nitrodehydrobenzene.During dehydroxylation in the absence of oxygen the proportion of the phenols corresponding to substitution of the hydrogen atom at the para position to the nitro group by the hydroxy group increases, and the degree of transformation of the inital compounds decreases. 2,4-Dinitrophenol is formed with a low yield during the reaction of 1,3-nitrobenzene and potassium hydroxide in the presence of oxygen or in an atmosphere of argon.
