1313429-24-1

Basic information

• Product Name: 2-methyl-3-(3-methoxyphenyl)pentanenitrile
• Synonyms: 2-methyl-3-(3-methoxyphenyl)pentanenitrile
• CAS NO: 1313429-24-1
• Molecular Weight: 203.284
• Mol File: 1313429-24-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-methyl-3-(3-methoxyphenyl)pentanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-3-(3-methoxyphenyl)pentanenitrile(1313429-24-1)
• EPA Substance Registry System: 2-methyl-3-(3-methoxyphenyl)pentanenitrile(1313429-24-1)

Safety Data

• Hazardous Substances Data: 1313429-24-1(Hazardous Substances Data)

Upstream product

• 773837-37-9 sodium cyanide 
• 1421260-91-4 1-(2-bromopentane)-3-methoxybenzene 
• 1421260-90-3 3-(3-methoxyphenyl)-2-pentanol 
• 2972-72-7 2-(3-methoxybenzylidene)malononitrile 
• 1313429-19-4 3-(3-methoxy-phenyl)-2-(toluene-4-sulfonyl)-pentanenitrile 
• 1313429-18-3 3-(3-methoxy-phenyl)-2-(toluene-4-sulfonyl)-pentanoic acid ethyl ester 
• 1313429-17-2 3-(1-bromopropyl)anisole 
• 1313429-15-0 2-[1-(3-methoxy-phenyl)-propyl]-malononitrile 
• 24393-44-0 2-cyano-3-(3-methoxyphenyl)acrylic acid ethyl ester 
• 591-31-1 3-methoxy-benzaldehyde 
• 1313429-14-9 2-cyano-3-(3-methoxy-phenyl)-pentanoic acid ethyl ester 
• 1313429-27-4 3-(3-methoxy-phenyl)-2-methyl-pentanoic acid ethyl ester 
• 1616-70-2 2-methyl-3-(3-methoxyphenyl)valeric acid 
• 1313429-25-2 2-cyano-3-(3-methoxy-phenyl)-2-methyl-pentanoic acid 

Downstream Products

• 515114-52-0 (±)-3-(1-(dimethylamino)-2-methylpentan-3-yl)phenol 
• 175591-09-0 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol hydrochloride 
• 175591-09-0 tapentadol hydrochloride 
• 175591-23-8 tapentadol 
• 175591-22-7 (βR,γR)-γ-ethyl-N,N,β-trimethyl-3-methoxybenzenepropanamine 
• 1616-70-2 2-methyl-3-(3-methoxyphenyl)valeric acid 
• 1313429-28-5 3-(3-methoxy-phenyl)-2-methyl-pentylamine 
• 1313429-30-9 2-methyl-3-(3-methoxyphenyl)valeryl chloride 
• 1313374-17-2 N,N-dimethyl-2-methyl-3-(3-methoxyphenyl)valeramide 
• 1313429-33-2 (R),(R)-3-(3-methoxy-phenyl)-2-methyl-pentanoic acid (R)-(+)-α-methylbenzylamine salt 
• 1313429-32-1 (αR,βR)-β-ethyl-3-methoxy-α-methylbenzenepropanoic acid 
• 1313429-37-6 (R),(R)-3-(3-methoxy-phenyl)-2-methyl-pentanoyl chloride 
• 1313374-09-2 (αR,βR)-β-ethyl-3-methoxy-N,N,α-trimethyl benzenepropanamide 
• 1322723-45-4 (+)-(2R,3S)-[3-(3-methoxyphenyl)-2-methylpentyl]-dimethylamine Hydrochloride 

Relevant articles and documents

Novel Intermediate Used for Preparing Tapentadol or Analogues Thereof

The invention discloses a novel intermediate for preparing tapentadol and analogues thereof, wherein the structural formula is shown as formula I or II, and the groups are defined as the specification. The invention further discloses a method for preparing the novel intermediate and use of the intermediate for preparing tapentadol and analogues thereof. The invention can remarkably improve the product yield and quality of tapentadol, reduce the production cost, and simplify the production procedure. The preparation process is environment friendly, thus more suitable for the requirements of industrial production.

PROCESS FOR THE PREPARATION OF 1-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES

A process for the preparation of 1-phenyl-3-dimethylaminopropane derivatives of formula (I) and its pharmaceutically acceptable salts thereof from cyano intermediate of formula (II), wherein R1 can be selected from -OR2, halo, -CH2OR2, -SR2, -SOR2, SO2R2, -SO3H, -NO2, -NR2R2', -CONR2R2', carboxylic esters, sulfonate esters or phosphate esters, R2 and R2' can be same or different, and can be selected from hydrogen, alkyl, aryl, aralkyl, heteroaryl, -COR2", -P03(R2")2 wherein R2" can be selected from alkyl, aryl, aralkyl, heteroaryl and the like.