132402-59-6

Basic information

• Product Name: 2(S)--3-phenylpropanimino ethyl ether
• Synonyms: 2(S)--3-phenylpropanimino ethyl ether
• CAS NO: 132402-59-6
• Molecular Weight: 292.378
• Mol File: 132402-59-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2(S)--3-phenylpropanimino ethyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 2(S)--3-phenylpropanimino ethyl ether(132402-59-6)
• EPA Substance Registry System: 2(S)--3-phenylpropanimino ethyl ether(132402-59-6)

Safety Data

• Hazardous Substances Data: 132402-59-6(Hazardous Substances Data)

Upstream product

• 88463-18-7 (S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropionamide 
• 17950-40-2 triethyloxonium hexaflourophosphate 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 63-91-2 L-phenylalanine 

Downstream Products

• 132402-74-5 2-<(S)-1-t-butyloxycarbonylamino-2-phenyl-ethyl>-4-methoxycarbonylthiazole 
• 161006-71-9 (S)-2-{[2-((S)-1-tert-Butoxycarbonylamino-2-phenyl-ethyl)-thiazole-4-carbonyl]-amino}-3-phenyl-propionic acid methyl ester 
• 131148-64-6 (S)-ethyl 2-(1-(tert-butoxycarbonylamino)-2-phenylethyl)thiazole-4-carboxylate 
• 276680-02-5 Boc-(S)-Phe-Thz-Phe-Pro-OMe 
• 161006-69-5 Boc-(S)-Phe-Thz-(S)-Pro-aThr-(R)-Val-Thz-OMe 
• 161006-68-4 C₃₈H₄₃N₇O₆S₂ 
• 120853-17-0 lissoclinamide 5 
• 132402-81-4 2-<(S)-1-t-butyloxycarbonylamino-2-phenyl-ethyl>-4-carboxythiazole 
• 132402-66-5 2-<(S)-1-t-butyloxycarbonylamino-2-phenyl-ethyl>-4-methoxycarbonyl-(R)-Δ2-thiazoline 

Relevant articles and documents

Oxidation of oxazolines and thiazolines to oxazoles and thiazoles. Application of the Kharasch-Sosnovsky reaction

Using a modification of the Kharasch-Sosnovsky reaction, the oxidation of oxazolines and thiazolines bearing a variety of 2-alkyl substituents (chiral and achiral) were smoothly oxidized to their corresponding oxazoles and thiazoles, respectively. The key feature involved in the successful implementation of this important oxidation was the use of a mixture of Cu(I) and Cu(II) salts to enhance the oxidation of the intermediate captodative radical, 24. The main limitation of this method was shown when the oxidation failed with oxazolines/thiazolines lacking the carboalkoxy group at C-4.