13435-08-0

Basic information

• Product Name: 1H-Benzimidazole,1-(trimethylsilyl)-(9CI)
• Synonyms: 1H-Benzimidazole,1-(trimethylsilyl)-(9CI)
• CAS NO: 13435-08-0
• Molecular Formula: C₁₀H₁₄N₂Si
• Molecular Weight: 190.31706
• Product Categories: BENZIMIDAZOLE
• Mol File: 13435-08-0.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazole,1-(trimethylsilyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,1-(trimethylsilyl)-(9CI)(13435-08-0)
• EPA Substance Registry System: 1H-Benzimidazole,1-(trimethylsilyl)-(9CI)(13435-08-0)

Safety Data

• Hazardous Substances Data: 13435-08-0(Hazardous Substances Data)

Upstream product

• 51-17-2 benzoimidazole 
• 10416-59-8 N,O-bis-(trimethylsilyl)-acetamide 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 403731-49-7 1-benzimidazolyl-2-O-acetyl-5-O-benzyl-3-O-(3,4-di-O-acetyl-2,6-di-O-benzyl-α-D-glucopyranosyl)-β-D-ribofuranose 
• 912561-29-6 1-(5-O-triphenylmethyl-2,3-O-isopropylidene-α-D-ribofuranosyl)benzimidazole 
• 912561-30-9 1-(5-O-triphenylmethyl-2,3-O-isopropylidene-β-D-ribofuranosyl)benzimidazole 
• 19018-22-5 1-allylbenzimidazole 
• 652968-46-2 1-(trifluoromethyl)-1H-benzo[d]imidazole 
• 46277-27-4 1-(2-hydroxyethoxymethyl)-benzimidazole 

Relevant articles and documents

SYNTHESIS OF N-GLYCOSIDES OF BENZIMIDAZOLE AND ITS DERIVATIVES

N-Benzimidazolylglucopyranosides were synthesized by condensation of N-trimethylsilyl derivatives of benzimidazole and its 2,5,6-trisubstituted derivatives with acetobromoglucose with subsequent removal of the protective groups.The β configuration of the glycoside center was proved on the basis of PMR spectral data.

Synthesis and Characterization of N-Trifluoromethyl N-Heterocyclic Carbene Ligands and Their Complexes

Starting from N-trifluoromethyl benzimidazole (1), a series of N-trifluoromethyl benzimidazolium salts 2a-f·HA have been prepared and fully characterized. These were engaged in the formation of [Ir(CO)2(NHC)Cl], [Rh(COD)(NHC)Cl], [Se(NHC)], and

Acyclic Analogs of Nucleosides. Synthesis of Hydroxyalkylbenzimidazoles and -Benzotriazoles

Condensation of trimethylsilyl derivatives of benzimidazole and benzotriazole with alkylating agents in the presence of trimethylsilyl trifluoromethanesulfonate or SnCl4, or direct alkylation of the sodium salts of benzimidazole and benzotriazole, gives 1-(2,3-dihydroxypropyl)-, 1-(3-hydroxy-2-oxabutyl)-, 1-(3-hydroxymethyl-4-hydroxy-2-oxabutyl)-, and 1-(1,5-dihydroxy-3-oxapent-2-yl)benzimidazole and -benzotriazole.

Chitosan–silica sulfate nanohybrid: a highly efficient and green heterogeneous nanocatalyst for the regioselective synthesis of N-alkyl purine, pyrimidine and related N-heterocycles via presilylated method

Abstract: The presilylation of purine and pyrimidine nucleobases as well as other related N-heterocycles with HMDS utilizing chitosan–silica sulfate nanohybrid (CSSNH) is described. CSSNH is proved to be a useful, highly efficient and eco-friendly heterogeneous nanohybrid catalyst for silylation of nucleobases. The presilylated nucleobases then underwent the reaction with different sources of carbon electrophiles to afford the desired N-alkyl-substituted derivatives in good-to-excellent yields. CSSNH exhibits several advantageous involving ease of handling and preparation, low cost, reusability and environmental benignity. These unique properties render the CSSNH to be an ideal candidate for use in green industrial processes. Graphic abstract: [Figure not available: see fulltext.].

Total synthesis of nucleobase-modified adenophostin A mimics

The adenophostins exhibit approximately 10-100 times higher receptor binding and Ca2+ mobilising potencies in comparison with the natural second messenger D-myo-inositol 1,4,5-trisphosphate [InS(1,4,5)P3]. Despite many synthetic atte