134807-64-0

Basic information

• Product Name: 2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate
• Synonyms: 2-(tert-butoxycarbonylamino)-3-phenylpropyl methanesulfonate
• CAS NO: 134807-64-0
• Molecular Formula: C₁₅H₂₃NO₅S
• Molecular Weight: 329.4118
• Mol File: 134807-64-0.mol
• Article Data: 40

Chemical Properties

• Boiling Point: 511.8°C at 760 mmHg
• Flash Point: 263.4°C
• Density: 1.185g/cm³
• Vapor Pressure: 1.37E-10mmHg at 25°C
• Refractive Index: 1.519
• CAS DataBase Reference: 2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate(134807-64-0)
• EPA Substance Registry System: 2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate(134807-64-0)

Safety Data

• Hazardous Substances Data: 134807-64-0(Hazardous Substances Data)

Upstream product

• 117049-14-6 tert-butyl N-[(1S)-2-hydroxy-1-phenylethyl]carbamate 
• 124-63-0 methanesulfonyl chloride 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 119153-87-6 (C₅H₉O₂)C₉H₉NO(O)(CO₂C₂H₅) 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 7143-01-3 Methanesulfonic anhydride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 3182-95-4 L-Phenylalaninol 
• 67729-36-6 Boc-Phe-O-COO-isoBu 
• 63-91-2 L-phenylalanine 
• 4522-04-7 ethyl N-{[(1,1-dimethylethyl)oxy]carbonyl}-L-phenylalaninate 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 

Downstream Products

• 155099-12-0 (2R,5S)-2-Benzyl-5-[(tert-butoxycarbonyl)amino]-6-phenyl-(E)-3-hexen-1-ol 
• 869377-95-7 (S)-tert-butyl 1-phenyl-3-(pyrrolidin-1-yl)propan-2-ylcarbamate 
• 606124-98-5 (S)-tert-butyl 1-morpholino-3-phenylpropan-2-ylcarbamate 
• 340161-69-5 tert-butyl (S)-(1-(dimethylamino)-3-phenylpropan-2-yl)carbamate 
• 1007877-57-7 ((S)-3-Amino-1-benzyl-propyl)-carbamic acid tert-butyl ester 
• 167421-83-2 tert-butyl N-[(1R)-1-methyl-2-phenylethyl]carbamate 
• 146552-72-9 (S)-2-(t-butoxycarbonylamino)-3-phenylpropylamine 
• 74822-65-4 (S)-(-)-1,2-diamino-3-phenylpropane dihydrochloride 
• 167867-38-1 N--<2(S)-benzyl>tauryl>-N'-tert-butyl-(4aS,8aS)-decahydro-3(S)-isoquinolinecarboxamide 
• 167867-57-4 (S)-2-Amino-N¹-[(S)-1-benzyl-2-((3S,4aS,8aS)-3-tert-butylcarbamoyl-octahydro-isoquinoline-2-sulfonyl)-ethyl]-succinamide 
• 167867-37-0 N--N'-tert-butyl-(4aS,8aS)-decahydro-3(S)-isoquinolinecarboxamide 
• 167867-49-4 (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfonylamino)-3-phenyl-propionic acid 
• 167867-55-2 (3S,4aS,8aS)-2-((S)-2-Amino-3-phenyl-propane-1-sulfonyl)-decahydro-isoquinoline-3-carboxylic acid tert-butylamide 
• 145641-43-6 N-phenylalanine methyl ester 

Relevant articles and documents

USP30 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of USP30, and the treatment of USP30-mediated disorders.

Asymmetric kinetic resolution of sulfides for the construction of unsymmetric sulfides and chiral 3,3-disubstituted oxindoles

A range of 3,3-disubstituted oxindoles accessed using para-quinone methides derived from isatins with thiols were used for the formation of unsymmetrical disulfides, and 3,3-disubstituted oxindoles with a chiral quaternary carbon center and unsymmetric di

Synthesis and antimalarial activity of new 4-aminoquinolines active against drug resistant strains

In the present study we have synthesized a new class of 4-aminoquinoline derivatives via replacement of the diethylamine functionality of chloroquine (CQ) with acyclic and/or cyclic amine groups containing basic tertiary terminal nitrogen and bioevaluated them for antimalarial activity against Plasmodium falciparum in vitro (CQ-sensitive strain-3D7 & CQ-resistant strain-K1) and Plasmodium yoelii in vivo (N-67 strain). Among the series, thirteen compounds showed superior antimalarial activity against K1 strain as compared to CQ. In addition, all these analogs showed 100% suppression of parasitaemia on day 4 in the in vivo mouse model against N-67 strain when administered orally. Further, biophysical studies suggest that these compounds act on the heme polymerization target.