13663-59-7

Basic information

• Product Name: N-CYCLOHEXYL-4-NITROANILINE
• Synonyms: Cyclohexylamine,N-(p-nitrophenyl)- (6CI,7CI,8CI); N-(4-Nitrophenyl)cyclohexylamine;N-Cyclohexyl-p-nitroaniline
• CAS NO: 13663-59-7
• Molecular Formula: C₁₂H₁₆N₂O₂
• Molecular Weight: 220.27
• Mol File: 13663-59-7.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-CYCLOHEXYL-4-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-CYCLOHEXYL-4-NITROANILINE(13663-59-7)
• EPA Substance Registry System: N-CYCLOHEXYL-4-NITROANILINE(13663-59-7)

Safety Data

• Hazardous Substances Data: 13663-59-7(Hazardous Substances Data)

Usage

General Description

N-CYCLOHEXYL-4-NITROANILINE is a chemical compound with the molecular formula C12H16N2O2 and a molecular weight of 220.27 g/mol. It is a nitroaniline derivative, which has a nitro group (-NO2) and an aniline group (-NH2) attached to a cyclohexyl ring. N-CYCLOHEXYL-4-NITROANILINE is commonly used as a chemical intermediate in the production of dyes, pigments, and pharmaceuticals. It is also known for its use in organic synthesis and as a precursor for the production of other important chemical compounds. N-CYCLOHEXYL-4-NITROANILINE is a yellow crystalline solid at room temperature and is considered to be harmful if swallowed, inhaled, or absorbed through the skin.

Upstream product

• 734-25-8 N-(4-nitrophenyl)-4-methylbenzenesulfonamide 
• 108-93-0 cyclohexanol 
• 636-98-6 p-nitrobenzene iodide 
• 766-93-8 N-cyclohexylformamide 
• 905718-45-8 [(4-nitrophenyl)(phenyl)iodonium trifluoromethanesulfonate] 
• 108-91-8 cyclohexylamine 
• 100-01-6 4-nitro-aniline 
• 24067-17-2 4-nitrophenylboronic acid 
• 110-83-8 cyclohexene 
• 586-78-7 para-nitrophenyl bromide 
• 73655-27-3 N-cyclohexylidene-4-nitroaniline 
• 10424-65-4 tetramethylammonium hydroxide dihydrate 
• 114274-07-6 4-(Cyclohexylideneamino)-1,2,4-triazole 
• 108-94-1 cyclohexanone 

Downstream Products

• 857610-31-2 N,N'-dicyclohexyl-N,N'-bis-(4-nitro-phenyl)-adipamide 
• 855928-69-7 acetic acid-(N-cyclohexyl-4-nitro-anilide) 

Relevant articles and documents

Amination of Aromatic Halides and Exploration of the Reactivity Sequence of Aromatic Halides

A base-promoted amination of aromatic halides has been developed using a limited amount of dimethylformamide (DMF) or amine as an amino source. Various aryl halides, including F, Cl, Br, and I, have been successfully aminated in good to excellent yields. Although the amination of aromatic halides with amines or DMF is usually considered as an aromatic nucleophilic substitution (SNAr) process, and the reactivity of an aromatic halide is F > Cl > Br > I, the reactivity of aromatic halides in this system was found to be I > Br a‰ F > Cl. This protocol also showed a good regioselectivity for multihalogenated aromatics. This protocol is valuable for industrial application due to the simplicity of operation, the unrestricted availability of amino sources and aromatic halides, transition metal-free conditions, no requirement for solvent, and scalability.

Functional ion liquid method for catalytic synthesis of amine compounds

The invention discloses a method for synthesizing an amine compound catalyzed by functionalized ionic liquid. According to the method, functionalized ionic liquid is used as a catalyst to catalyze N-alkylation of amine and alcohol to synthesize corresponding compound derivatives. Acid functionalized ionic liquid is used as the catalyst to synthesize a series of compounds of amine. The method has the following advantages: a catalytic system is a metal-free system; the usage amount of the catalyst is small, and the catalyst has high catalytic activity, good stability and low corrosivity; operation is simple, and reaction is mild; post-treatment is easy, and the catalyst can be cyclically used.

Carbon-coated magnetic palladium: Applications in partial oxidation of alcohols and coupling reactions

A carbon-coated magnetic Pd catalyst has been synthesized via in situ generation of nanoferrites and incorporation of carbon from renewable cellulose via calcination; the catalyst can be used for oxidation of alcohols, amination reaction and arylation of aryl halides (cross-coupling reaction). the Partner Organisations 2014.