13726-21-1

Basic information

• Product Name: (4-CHLORO-3-METHOXYPHENYL)ACETONITRILE
• Synonyms: (4-CHLORO-3-METHOXYPHENYL)ACETONITRILE;RARECHEM AL MP 0203;2-(4-Chloro-3-Methoxyphenyl)acetonitrile;2-(4-Chloro-3-methoxyphenyl)
• CAS NO: 13726-21-1
• Molecular Formula: C₉H₈ClNO
• Molecular Weight: 181.62
• Mol File: 13726-21-1.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (4-CHLORO-3-METHOXYPHENYL)ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-CHLORO-3-METHOXYPHENYL)ACETONITRILE(13726-21-1)
• EPA Substance Registry System: (4-CHLORO-3-METHOXYPHENYL)ACETONITRILE(13726-21-1)

Safety Data

• Hazardous Substances Data: 13726-21-1(Hazardous Substances Data)

Usage

General Description

(4-CHLORO-3-METHOXYPHENYL)ACETONITRILE is a chemical compound with the molecular formula C9H8ClNO. It is a nitrile derivative of 4-chloro-3-methoxyphenylacetic acid and is used in the synthesis of various pharmaceutical compounds and agrochemicals. It is a white to off-white crystalline solid with a melting point of 67-68°C. (4-CHLORO-3-METHOXYPHENYL)ACETONITRILE is mainly used as an intermediate in the production of active pharmaceutical ingredients and can also be used as a building block in organic synthesis. It is important to handle and store this chemical with proper safety measures in place due to its potential hazardous nature.

Upstream product

• 143-33-9 sodium cyanide 
• 103347-14-4 4-(bromomethyl)-1-chloro-2-methoxybenzene 
• 7677-24-9 trimethylsilyl cyanide 
• 13726-18-6 1-chloro-4-chloromethyl-2-methoxybenzene 
• 615-74-7 2-chloro-5-methylphenol 
• 73909-16-7 2-chloro-5-methylanisole 
• 773837-37-9 sodium cyanide 
• 97-52-9 2-methoxy-4-nitrophenylamine 
• 13726-14-2 4-chloro-m-anisidine 
• 13726-17-5 (4-chloro-3-methoxyphenyl)methan-1-ol 
• 13726-16-4 4-chloro-3-methoxybenzaldehyde 
• 151-50-8 potassium cyanide 
• 85740-98-3 4-chloro-3-methoxybenzoic acid 
• 1009-36-5 2-chloro-5-nitroanisole 

Downstream Products

• 13726-19-7 2-(4-chloro-3-methoxyphenyl)acetic acid 
• 867366-60-7 ethyl 4-chloro-3-methoxyphenylmethylimidate hydrochloride 
• 13726-25-5 3-Methoxy-4-chlor-phenylacetylhomoveratrylamin 
• 850564-15-7 2-(4-Chloro-3-methoxy-phenyl)-2-methyl-propionitrile 
• 936727-47-8 2-(3-(benzyloxy)-4-chlorophenyl)acetonitrile 
• 672931-86-1 (4-Chloro-3-hydroxyphenyl) acetic acid methyl ester 
• 1184103-08-9 12-benzyl-3-(4-chloro-3-methoxyphenyl)-8-(phenylsulfonyl)-2-pyridin-4-yl-7,8,9,10-tetrahydro-6H-7,10-epiminocyclohepta[e]pyrazolo[1,5-a]pyrimidine 
• 1184103-00-1 2-chloro-5-[12-methyl-8-(phenylsulfonyl)-2-pyridin-4-yl-7,8,9,10-tetrahydro-61-1-7,10-epiminocyclo-hepta[e]pyrazolo[1,5-a]pyrimidin-3-yl]phenol 
• 1184103-03-4 methyl 3-(4-chloro-3-hydroxyphenyl)-12-methyl-2-pyridin-4-yl-7,8,9,10-tetrahydro-6H-7,10-epiminocyclohepta-[e]pyrazolo[1,5-a]pyrimidine-8-carboxylate 
• 1184103-06-7 2-chloro-5-[8-(hydroxymethyl)-12-methyl-2-pyridin-4-yl-7,8,9,10-tetrahydro-6H-7,10-epiminocyclo-hepta[e]pyrazolo[1,5-a]pyrimidin-3-yl]phenol 
• 1184103-49-8 3-chloro-2-(4-chloro-3-methoxyphenyl)-3-pyridin-4-ylacrylonitrile 
• 1134598-81-4 5-(3-amino-5-pyridin-4-yl-1H-pyrazol-4-yl)-2-chlorophenol 
• 1134598-79-0 4-(4-chloro-3-methoxyphenyl)-5-pyridin-4-yl-1H-pyrazol-3-amine 
• 1184103-48-7 2-(4-chloro-3-methoxyphenyl)-3-oxo-3-pyridin-4-ylpropanenitrile 

Relevant articles and documents

HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME

A heterocyclic compound represented by formula XI, a pharmaceutically acceptable salt, a solvate, or a solvate of a pharmaceutically acceptable salt thereof, use thereof, and a composition containing the same. The compound is novel in structure and has good STAT5 inhibitory activity.

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.