1380920-99-9

Upstream product

• 1380920-97-7 4-chloro-5-(3,3-difluoropyrrolidin-1-yl)-2-nitroaniline 
• 1242269-88-0 N-(4-chloro-3-isothiocyanatobenzyl)-2,2-dimethyl-propionamide 
• 1360702-28-8 N-(3-amino-4-chlorobenzyl)pivalamide 
• 1360702-27-7 N-(4-chloro-3-nitrobenzyl)-2,2-dimethyl-propionamide 
• 6641-64-1 4,5-dichloro-2-nitroaniline 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 1380919-16-3 N-{4-chloro-3-[6-chloro-5-(3,3-difluoropyrrolidin-1-yl)-1H-benzo[d]imidazol-2-ylamino]benzyl}-2,2-dimethyl-propionamide 

Relevant academic research and scientific papers

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), to pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R3, R4, R6, R2, R7, R8, R9, Ra, Rb have meanings given in the description.