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1221172-02-6

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1221172-02-6 Usage

Description

6-chloro-2-(trifluoromethoxy)-3-(trimethylsilyl)pyridine is a chemical compound featuring a chloro group and a trifluoromethoxy group on a pyridine ring, along with a trimethylsilyl group. 6-chloro-2-(trifluoroMethoxy)-3-(triMethylsilyl)pyridine is known for its role in enhancing the stability and reactivity of molecules in organic synthesis.

Uses

Used in Organic Synthesis:
6-chloro-2-(trifluoromethoxy)-3-(trimethylsilyl)pyridine is used as a reagent for the introduction of a trimethylsilyl group onto a molecule, which can help to increase its stability and/or reactivity.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-chloro-2-(trifluoromethoxy)-3-(trimethylsilyl)pyridine is utilized for the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemicals:
6-chloro-2-(trifluoromethoxy)-3-(trimethylsilyl)pyridine is employed in the field of agrochemicals for the synthesis of new active ingredients, potentially enhancing the effectiveness of agricultural products.
Used in Material Science:
6-chloro-2-(trifluoroMethoxy)-3-(triMethylsilyl)pyridine has potential applications in material science, where it may contribute to the development of new materials with specific properties.
Used as a Building Block:
6-chloro-2-(trifluoromethoxy)-3-(trimethylsilyl)pyridine serves as a building block in the production of various organic compounds, facilitating the creation of a wide range of chemical products.

Check Digit Verification of cas no

The CAS Registry Mumber 1221172-02-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,1,1,7 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1221172-02:
(9*1)+(8*2)+(7*2)+(6*1)+(5*1)+(4*7)+(3*2)+(2*0)+(1*2)=86
86 % 10 = 6
So 1221172-02-6 is a valid CAS Registry Number.

1221172-02-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [6-chloro-2-(trifluoromethoxy)pyridin-3-yl]-trimethylsilane

1.2 Other means of identification

Product number -
Other names 6-chloro-2-(trifluoromethoxy)-3-(trimethylsilyl)pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1221172-02-6 SDS

1221172-02-6Relevant articles and documents

2-AMINO-N-PHENYL-NICOTINAMIDES AS NAV1.8 INHIBITORS

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Page/Page column 88, (2020/05/28)

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Nav1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Nav1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.

Tri- and difluoromethoxylated N-based heterocycles ? Synthesis and insecticidal activity of novel F3CO- and F2HCO-analogues of Imidacloprid and Thiacloprid

Landelle, Gregory,Schmitt, Etienne,Panossian, Armen,Vors, Jean-Pierre,Pazenok, Sergiy,Jeschke, Peter,Gutbrod, Oliver,Leroux, Frédéric R.

, p. 155 - 165 (2017/09/07)

The preparation of F3CO- and F2HCO-analogues of Imidacloprid and Thiacloprid and the evaluation of their biological activity have been performed. For this purpose, a first synthetic approach allowed the preparation of a desired F3CO-containing key intermediate. To allow a facile access to the second F2HCO-containing key intermediate, the difluoromethylation of hydroxylated N-based heterocycles has been developed using difluoromethyl triflate (a liquid non-ODS reagent) under air in aqueous conditions and with very short reaction time. The broad diversity of compatible heterocycles includes a large series of substituted hydroxy-pyridines, but also ?pyrazoles, ?pyrazine, ?pyridazine, and ?quinolines. The couplings of both key intermediates with the required 4,5-dihydro-N-nitro-1H-imidazol-2-amine and [N(Z)]-N-2-thiazolidinylidene-cyanamide were successfully achieved using literature conditions. This work enables the preparation of valuable building blocks, which could lead to the discovery of new bioactive entities.

1-(6-MEMBERED AZO-HETEROCYCLIC)-2,5-DIHYDRO-1H-PYRROL-2-ONE DERIVATIVES AS ANTI-HEPATITIS C VIRUS, THE PHARMACEUTICAL COMPOSITION THEREOF AND THEIR THERAPEUTIC USE

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, (2012/07/27)

The present invention concerns 1-(6-memberedazo-heterocyclic)-2,5-dihydro–1H–pyrrol–2-one compoundsof the following formula (I) or a salt, solvate, tautomer, isotope, enantiomer, diastereoisomer or racemic mixture thereof: the pharmaceutical composition thereof and their therapeutic use as inhibitors of Hepatitis C virus.

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