139399-68-1

Upstream product

• 5467-64-1 2-acetamidophenyl acetate 
• 3296-05-7 1-azido-4-chlorobenzene 
• 64-19-7 acetic acid 
• 614-80-2 2-(acetylamino)phenol 
• 539-03-7 N-(4-chlorophenyl)acetamide 
• 95-55-6 2-amino-phenol 
• 59130-68-6 N,N,O-Triacetyl-2-aminophenol 
• 67-66-3 chloroform 
• 7782-50-5 chlorine 

Downstream Products

• 16323-09-4 N-(4-chloro-2-hydroxyphenyl)acetamide 
• 28443-50-7 2-amino-5-chlorophenol 

Relevant academic research and scientific papers

Reexamination of the Thermolytic Rearrangement of 4-Halophenyl Azides to 2-Aminophenols and other Products

The halogenation of derivatives of 2-aminophenol with N-chloro- and N-bromosuccinimides at ambient temperatures in acetic acid was studied.With the necessary compounds available, a reexamination of the thermolytic rearrangement of 2-halophenyl azides to 2-aminophenols and other products was undertaken.It is certain that the rearrangement of 4-halophenyl azides to 2-aminophenols occurs but the products identified in this study differ significantly from those reported previously by Suschitzky et al. (1963, 1966). Keywords: Acetylated-2-amino-5-halophenols; 2-Acetamido-5-haloanisoles; 6-Halo-2-methylbenzoxazoles; 6-Halobenzoxazolones; 6-Halotriacetylaminophenols; 1H-NMR spectra; Fungicidal activity.

Direct ortho-acetoxylation of anilides via palladium-catalyzed sp 2 C-H bond oxidative activation

(Chemical Equation Presented) Various anilides have been directly ortho-acetoxylated through a Pd(OAc)2-catalyzed C-H bond activation process. The amide group in anilides was found to functionalize as an elegant directing group to convert aromatic sp2 C-H bonds into C-O bonds in high regioselectivity with acetic acid as the acetate source and K 2S2O8 as the oxidant.