1394124-19-6

Basic information

• Product Name: (E)-methyl 2-(2-(2-(4-chlorophenyl)-6-(2-cyanophenoxy)pyrimidin-4-yloxy)phenyl)-3-(methoxy)acrylate
• Synonyms: (E)-methyl 2-(2-(2-(4-chlorophenyl)-6-(2-cyanophenoxy)pyrimidin-4-yloxy)phenyl)-3-(methoxy)acrylate
• CAS NO: 1394124-19-6
• Molecular Weight: 513.937
• Mol File: 1394124-19-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-methyl 2-(2-(2-(4-chlorophenyl)-6-(2-cyanophenoxy)pyrimidin-4-yloxy)phenyl)-3-(methoxy)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl 2-(2-(2-(4-chlorophenyl)-6-(2-cyanophenoxy)pyrimidin-4-yloxy)phenyl)-3-(methoxy)acrylate(1394124-19-6)
• EPA Substance Registry System: (E)-methyl 2-(2-(2-(4-chlorophenyl)-6-(2-cyanophenoxy)pyrimidin-4-yloxy)phenyl)-3-(methoxy)acrylate(1394124-19-6)

Safety Data

• Hazardous Substances Data: 1394124-19-6(Hazardous Substances Data)

Upstream product

• 614-75-5 2-Hydroxyphenylacetic acid 
• 19068-82-7 2-(4-chloro-phenyl)-4,6-diethoxy-pyrimidine 
• 14401-51-5 4-chlorobenzamidine hydrochloride 
• 26870-72-4 4,6-dichloro-2-(4-chlorophenyl)-pyrimidine 
• 1394124-10-7 methyl 2-(2-(6-chloro-2-(4-chlorophenyl)pyrimidin-4-yloxy)phenyl)-3,3-dimethoxypropanoate 
• 83217-77-0 2-p-chlorophenyl-4,6-dihydroxypyrimidine 
• 175971-61-6 2-(2-hydroxyphenyl)-3,3-dimethoxypropionic acid methyl ester 
• 40800-90-6 3-(α-methoxy)methylene benzofuran-2-(3H)-ketone 
• 611-20-1 salicylonitrile 
• 1394124-11-8 (E)-methyl 2-(2-(6-chloro-2-(4-chlorophenyl)pyrimidin-4-yloxy)phenyl)-3-(methoxy)acrylate 

Relevant articles and documents

Synthesis and antifungal activities of new type β-methoxyacrylate- based strobilurin analogues

Strobilurins have become one of the most important classes of agricultural fungicides. To discover new strobilurin derivatives with high activity against resistant pathogens, a series of novel β-methoxyacrylate analogues were designed and synthesized by integrating substituted pyrimidine with a strobilurin pharmacophore. The compounds were confirmed and characterized by infrared, 1H nuclear magnetic resonance, elemental analysis and mass spectroscopy. The bioassays indicated that most of the compounds 1 exhibited potent antifungal activity against Colletotrichum orbiculare, Botrytis cinerea Pers and Phytophthora capsici Leonian at the concentration of 50 μg/mL. Exhilaratingly, compound 1a (R=methyl) showed better antifungal activity against all the tested fungi than the commercial strobilurin fungicide azoxystrobin. Copyright