140621-52-9

Usage

Uses

Used in Scientific Research:
1-(4-iodophenyl)-N,N-dimethylmethanamine is used as a research tool for studying the functions and interactions of monoamine neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. Its application aids in understanding the complex mechanisms underlying various neurological and psychiatric conditions.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 1-(4-iodophenyl)-N,N-dimethylmethanamine is used as a compound with potential therapeutic applications. Its role as a strong releaser of monoamine neurotransmitters suggests that it may contribute to the development of new medications for the treatment of psychiatric disorders.
Used in Treatment of Psychiatric Disorders:
Although still under investigation, 1-(4-iodophenyl)-N,N-dimethylmethanamine may be used as a therapeutic agent for certain psychiatric conditions. Its ability to modulate the levels of critical neurotransmitters could potentially offer new treatment options for patients suffering from these disorders.

Upstream product

• 16004-15-2 1-bromomethyl-4-iodobenzene 
• 124-40-3 dimethyl amine 
• 619-58-9 4-iodobenzoic acid 
• 506-59-2 N,N-dimethylammonium chloride 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 109-89-7 diethylamine 
• 624-31-7 4-tolyl iodide 
• 100-97-0 hexamethylenetetramine 

Downstream Products

• 16004-15-2 1-bromomethyl-4-iodobenzene 
• 1467-79-4 NCNMe₂ 
• 36874-95-0 4-(dimethylaminomethyl)benzaldehyde 
• 1391916-73-6 C₃₉H₄₀BF₂IN₄ 
• 1247001-32-6 N,N-dimethyl-1-(4-acetylenylphenyl)methylamine 

Relevant academic research and scientific papers

Chemoselective Reduction of Tertiary Amides by 1,3-Diphenyl disiloxane (DPDS)

A convenient procedure for the chemoselective reduction of tertiary amides at room temperature in the presence of air and moisture using 1,3-diphenyldisiloxane (DPDS) is developed. The reaction conditions tolerate a significant number of functional groups including esters, nitriles, secondary amides, carbamates, sulfoxides, sulfones, sulfonyl fluorides, halogens, aryl-nitro groups, and arylamines. The conditions reported are the mildest to date and utilize EtOAc, a preferred solvent given its excellent safety profile and lower environmental impact. The ease of setup and broad chemoselectivity make this method attractive for organic synthesis, and the results further demonstrate the utility of DPDS as a selective reducing agent.

NOVEL ANTIBIOTICS

Novel aryl compounds or pharmaceutically acceptable salts thereof, and uses of the same for the treatment of Gram-negative infections.

HETERO-HALO INHIBITORS OF HISTONE DEACETYLASE

This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.

Orally bioavailable factor Xa inhibitors containing alpha-substituted gem-dimethyl P4 moieties

In an effort to identify a potential back-up to apixaban (Eliquis), we explored a series of diversified P4 moieties. Several analogs with substituted gem-dimethyl moieties replacing the terminal lactam of apixaban were identified which demonstrated potent

Water-soluble red-emitting distyryl-borondipyrromethene (BODIPY) dyes for biolabeling

A series of water-soluble red-emitting distyryl-borondipyrromethene (BODIPY) dyes were designed and synthesized by using three complementary approaches aimed at introducing water-solubilizing groups on opposite faces of the fluorescent core to reduce or c

ISOTOPE EXCHANGE OF IODINE IN INACTIVATED IODINE DERIVATIVES OF BENZENE, CATALYZED BY COPPER SALT

The isotope exchange of iodine in some aromatic iodine compounds was investigated in the presence of copper salts in various solvents at 76.5 deg C.It was shown that monovalent copper is responsible for the catalysis during isotope exchange.The isotope exchange is due to intramolecular coordination of the Cu1+ ion with a molecule of the aromatic iodine compounds.A scheme for the isotope exchange of iodine in iodoarenes in the presence of copper salts, using the idea of a one-electron transfer and coordination action between the d10 metals and the ? systems, is proposed and discussed.

Novel quaternary ammonium salts, compositions and methods for their use

Para-iodobenzyltrimethylammonium iodide is useful as an intermediate in the manufacture of the corresponding compounds wherein the para-iodo atom is enriched with an 123 iodine, 125 iodine or 131 iodine isotope. These radi