14252-80-3

Basic information

• Product Name: Bupivacaine hydrochloride
• Synonyms: BUPIVACAINE HYDROCHLORIDE;(+,-)-1-butyl-2’,6’-pipecoloxylididemonohydrochloride,monohydrate;1-butyl-2’,6’-pipecoloxylididehydrochloride(+-);2-piperidinecarboxamide,1-butyl-n-(2,6-dimethylphenyl)-monohydrochloride,m;ah-2250;marcainehydrochloride;dl-1-n-Butylpiperidine-2-carboxylic Acid 2,6-Dimethylanilide Hydrochloride;Sensorcaine
• CAS NO: 14252-80-3
• Molecular Formula: C18H28N2O.ClH
• Molecular Weight: 324.89
• EINECS: 241-917-8
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Sodium channel;Amines;Aromatics;Heterocycles;TAXOL
• Mol File: 14252-80-3.mol

Chemical Properties

• Melting Point: 249-2510C
• Boiling Point: 423.4oC at 760 mmHg
• Flash Point: 209.9oC
• Appearance: /
• Storage Temp.: Refrigerator
• CAS DataBase Reference: Bupivacaine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Bupivacaine hydrochloride(14252-80-3)
• EPA Substance Registry System: Bupivacaine hydrochloride(14252-80-3)

Safety Data

• Hazard Codes: T+
• Statements: 26/27/28
• Safety Statements: 22-36/37/39-45
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: TK6125000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 14252-80-3(Hazardous Substances Data)

Usage

Uses

Sodium channel blocker, local anesthetic

Brand name

Marcaine (Hospira); Sensorcaine (AstraZeneca).

Uses

antineoplastic

Chemical Properties

White Solid

InChI:InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H

Upstream product

• 142525-11-9 ELVIS 
• 142525-10-8 glutamyl-lysyl-valyl-isoleucyl-serine 
• 142524-71-8 2-Bromo-6-(1-ethoxyethoxy)naphthalene 95+% 
• 14252-46-1 2,2-bis(phenylthio)propane 
• 14252-45-0 Acetone diethyl dithioacetal 
• 14252-42-7 bicyclo[4.2.1]nonan-9-one 
• 142523-69-1 1-(benzyloxy)-2-iodobenzene 
• 142523-67-9 3,4-DICHLOROBENZYL IODIDE 
• 142523-38-4 L-690,330 
• 14252-32-5 1-phenylhex-1-yn-3-one 
• 142523-14-6 1-[(4-HYDROXYPHENOXY)ETHYLIDENE]BIS[PHOSPHINYLIDYNEBIS(OXYMETHYLENE)]-2,2-DIMETHYLPROPANOATE 
• 142522-81-4 SODIUM (R)-1-[(1-{3-[2-(7-CHLORO-2-QUINOLYL)VINYL]PHENYL}-3-[2-(1-HYDROXY-1- 
• 14252-27-8  
• 142522-28-9 MONTELUKAST 

Downstream Products

• 14252-84-7 (E)-3-hexenyl)dihydro-5-methylfuran-2(3H)-one 
• 142528-74-3 1,3,5-Triazine-2,4(1H,3H)-dione,6-ethyldihydro-6-methyl-(9CI) 
• 142529-00-8 1H-Pyrrole-2-carboxylic acid, 1-[(2-nitrophenyl)sulfonyl]-, ethyl este r 
• 142529-01-9 1H-Pyrrole-2-carboxylic acid, 1-[(2-aminophenyl)sulfonyl]-, ethyl este r 
• 142529-65-5 N-(2-chlorophenyl)-2-[(4-ethyl-5-pyridin-3-yl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide 
• 142529-91-7 N-(4-bromophenyl)-2-{[4-cyclohexyl-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide 
• 142-53-0 Hexanedioic acid,1,6-bis(8-methylnonyl) ester 
• 1425310-59-3 7-Iodoquinazoline 
• 14253-18-0 1-Methyl-N-(3,3,4,4-tetraphenyloxetan-2-ylidene)-1-propanamine 
• 142532-81-8 Ethanone, 1-(3,3-dimethyloxiranyl)-, (+)- (9CI) 
• 142532-82-9 Ethanone, 1-(3,3-dimethyloxiranyl)-, (-)- (9CI) 
• 142533-06-0 cholest-8(14)-ene-3,15,26-triol 
• 1425334-68-4 4-iodopyridin-3-yl diMethylcarbaMate 
• 1425334-70-8 5-(1-(tert-butoxycarbonyl)pyrrolidin-2-yl)pyridin-3-ylboronic acid 

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Intraoperative Infiltration of Liposomal Bupivacaine vs Bupivacaine hydrochloride (cas 14252-80-3) for Pain Management in Primary Total Hip Arthroplasty: A Prospective Randomized Trial07/19/2019

BackgroundPain management after total hip arthroplasty is well studied. Nevertheless, there is no consensus regarding the “cocktail” to use in periarticular infiltration (PAI). Liposomal bupivacaine (LB) is a slow release local anesthetic that can be infiltrated during surgery. In this study, ...detailed

Distribution of Bupivacaine hydrochloride (cas 14252-80-3) after sciatic and femoral nerve blocks in cats: A magnetic resonance imaging study07/18/2019

The objective of this study was to evaluate the distribution of bupivacaine hydrochloride using magnetic resonance imaging (MRI) after electrical nerve stimulator (ENS)-guided sciatic (ScN) and femoral (FN) nerve blocks in cats. Six adult cats (body weight 4.8 ± 0.6 kg) were anesthetized with a...detailed

Liposomal Bupivacaine Versus Bupivacaine hydrochloride (cas 14252-80-3) with Lidocaine during Midurethral Sling Placement: A Randomized Controlled Trial07/17/2019

ABSTRACTStudy ObjectiveTo study the effects of liposomal bupivacaine (LB) compared with bupivacaine hydrochloride with lidocaine on postoperative day 1 pain scores.detailed

Neurotoxicity of intraneural injection of bupivacaine liposome injectable suspension versus Bupivacaine hydrochloride (cas 14252-80-3) in a porcine model07/16/2019

ObjectiveTo test whether neurotoxic effects of a bupivacaine liposome injectable suspension differ from those of a standard formulation of bupivacaine hydrochloride (HCl) after intraneural injection into the sciatic nerves in pigs.detailed