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14252-80-3

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Bupivacaine hydrochloride
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14252-80-3 Usage

Uses

Sodium channel blocker, local anesthetic

Biological Functions

Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine.

Uses

antineoplastic

Chemical Properties

White Solid

Brand name

Marcaine (Hospira); Sensorcaine (AstraZeneca).
InChI:InChI=1S/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H

14252-80-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Bupivacaine Hydrochloride

1.2 Other means of identification

Product number -
Other names Bupivacaine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14252-80-3 SDS

14252-80-3Related news

Intraoperative Infiltration of Liposomal Bupivacaine vs Bupivacaine hydrochloride (cas 14252-80-3) for Pain Management in Primary Total Hip Arthroplasty: A Prospective Randomized Trial07/19/2019

BackgroundPain management after total hip arthroplasty is well studied. Nevertheless, there is no consensus regarding the “cocktail” to use in periarticular infiltration (PAI). Liposomal bupivacaine (LB) is a slow release local anesthetic that can be infiltrated during surgery. In this study, ...detailed

Distribution of Bupivacaine hydrochloride (cas 14252-80-3) after sciatic and femoral nerve blocks in cats: A magnetic resonance imaging study07/18/2019

The objective of this study was to evaluate the distribution of bupivacaine hydrochloride using magnetic resonance imaging (MRI) after electrical nerve stimulator (ENS)-guided sciatic (ScN) and femoral (FN) nerve blocks in cats. Six adult cats (body weight 4.8 ± 0.6 kg) were anesthetized with a...detailed

Liposomal Bupivacaine Versus Bupivacaine hydrochloride (cas 14252-80-3) with Lidocaine during Midurethral Sling Placement: A Randomized Controlled Trial07/17/2019

ABSTRACTStudy ObjectiveTo study the effects of liposomal bupivacaine (LB) compared with bupivacaine hydrochloride with lidocaine on postoperative day 1 pain scores.detailed

Neurotoxicity of intraneural injection of bupivacaine liposome injectable suspension versus Bupivacaine hydrochloride (cas 14252-80-3) in a porcine model07/16/2019

ObjectiveTo test whether neurotoxic effects of a bupivacaine liposome injectable suspension differ from those of a standard formulation of bupivacaine hydrochloride (HCl) after intraneural injection into the sciatic nerves in pigs.detailed

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