14315-15-2

Basic information

• Product Name: 7-METHYL-BENZO[B]THIOPHENE
• Synonyms: 7-METHYL-BENZO[B]THIOPHENE;7-METHYLBENZOTHIOPHENE;7-METHYL-1-BENZOTHIOPHENE
• CAS NO: 14315-15-2
• Molecular Formula: C₉H₈S
• Molecular Weight: 148.22
• Mol File: 14315-15-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 243°C at 760 mmHg
• Flash Point: 72.4°C
• Appearance: /
• Density: 1.146g/cm³
• Vapor Pressure: 0.0514mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 7-METHYL-BENZO[B]THIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHYL-BENZO[B]THIOPHENE(14315-15-2)
• EPA Substance Registry System: 7-METHYL-BENZO[B]THIOPHENE(14315-15-2)

Safety Data

• Hazardous Substances Data: 14315-15-2(Hazardous Substances Data)

Usage

General Description

7-Methyl-benzo[b]thiophene, also known as 7MBT, is a chemical compound belonging to the class of benzo[b]thiophenes. It is a pale yellow liquid with a boiling point of 187°C and a molecular weight of 150.2 g/mol. 7-Methyl-benzo[b]thiophene is primarily used as a building block in the synthesis of various organic compounds and has applications in the pharmaceutical and agrochemical industries. It is also used as a flavoring agent and in the production of dyes and pigments. This chemical is known for its strong odor and is considered to be hazardous if not handled properly.

InChI:InChI=1/C9H8S/c1-7-3-2-4-8-5-6-10-9(7)8/h2-6H,1H3

Upstream product

• 51830-52-5 o-tolylsulfanyl-acetaldehyde dimethylacetal 
• 6007-83-6 2,3-thiophenedicarboxylic acid anhydride 
• 542-92-7 cyclopenta-1,3-diene 
• 95-46-5 2-methylphenyl bromide 
• 74-86-2 acetylene 
• 86119-84-8 phosphoric acid 
• 137-06-4 2-thiocresol 
• 4923-87-9 5-bromobenzo[b]thiophene 
• 13061-96-6 dihydroxy-methyl-borane 
• 91905-69-0 (o-tolylthio)acetaldehyde diethylacetal 
• 68670-99-5 7-Methylbenzothiophen-3(2H)-on 
• 5380-42-7 thiophene-2-carboxylic acid methyl ester 
• 37610-80-3 1,3-dioxolan-2-ylethylmagnesium bromide 

Downstream Products

• 10133-24-1 7-(bromomethyl)benzothiophene 
• 22720-97-4 2-(4-methyl)phenyl-6-methylbenzothiophene 
• 80823-97-8 7-methyl-3-(p-tolyl)-2,3-dihydrobenzothiophen 

Relevant articles and documents

Enantioselective hydroarylation or hydroalkenylation of benzo[b]thiophene 1,1-dioxides with organoboranes

An efficient protocol for the asymmetric hydroarylation and hydroalkenylation of benzo[b]thiophene 1,1-dioxides with organoboranes has been developed. The combination of a rhodium(I) precatalyst and a chiral diene ligand constitutes the catalytic system, which enables the facile synthesis of 2,3-dihydrobenzo[b]thiophene 1,1-dioxides in good yields with high enantioselectivities. The merging of this asymmetric hydroarylation with the downstream alkylations delivers 2,3-dihydrobenzo[b]thiophene 1,1-dioxides that contain two continuous quaternary stereocenters with high enantioselectivities in a diastereodivergent manner.

HIV integrase inhibitors

The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.

BICYCLIC HETEROCYCLES AS HIV INTEGRASE INHIBITORS

The invention encompasses a series cyclic bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.