143615-31-0

Basic information

• Product Name: 1,2-Butanediol, 4-phenyl-, (R)-
• CAS NO: 143615-31-0
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 143615-31-0.mol
• Article Data: 69

Chemical Properties

• CAS DataBase Reference: 1,2-Butanediol, 4-phenyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Butanediol, 4-phenyl-, (R)-(143615-31-0)
• EPA Substance Registry System: 1,2-Butanediol, 4-phenyl-, (R)-(143615-31-0)

Safety Data

• Hazardous Substances Data: 143615-31-0(Hazardous Substances Data)

Usage

Chirality

(R)configuration

Physical state

Colorless, viscous liquid

Uses

a. Solvent
b. Production of pharmaceuticals and chemicals

Synthesis

Used in the synthesis of chiral drug molecules

Biological effects

a. Mild sedative
b. Hypnotic effects
c. Minor CNS depressant

Applications

a. Pharmaceutical industry
b. Cosmetic industry
c. Chemical industry

Versatility

Due to its chiral nature and diverse properties, it has potential applications in various industries.

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 50-00-0 formaldehyd 
• 16939-57-4 (E)-buta-1,3-dienylbenzene 
• 768-56-9 4-Phenylbut-1-ene 
• 134916-70-4 4-phenylbutane-1,2-diyl diacetate 
• 6921-34-2 benzylmagnesium chloride 
• 64920-29-2 2-oxo-4-phenylbutanoic acid ethyl ester 
• 1192826-26-8 4-phenethyl-1,3-dioxolane 
• 100-39-0 benzyl bromide 
• 93921-85-8 ethyl 2-hydroxy-4-phenylbutanoate 
• 134134-76-2 (4,4-difluorobut-3-en-1-yl)benzene 
• 90315-82-5 ethyl (R)-2-hydroxy-4-phenylbutyrate 
• 118487-52-8 (E)-2-oxo-4-phenylbut-3-en-1-yl acetate 
• 209864-30-2 (2R,3E)-4-phenylbut-3-ene-1,2-diol 

Downstream Products

• 19969-15-4 4-Phenyl-butan-diol-(1,2)-bis-phenyl-urethan 
• 124988-64-3 (S)-4-phenyl-1,2-butanediol 
• 173917-44-7 1-(tert-butyl-dimethylsilyloxy)-4-phenylbutan-2-ol 
• 851372-04-8 (2R)-2-hydroxy-4-phenylbutyl 4-methylbenzenesulfonate 
• 862464-35-5 (R)-6-phenethyldihydropyran-2,4-dione 
• 862464-34-4 methyl (5R)-5-hydroxy-3-oxo-7-phenylheptanoate 
• 198561-33-0 (3R)-3-hydroxy-5-phenylpentanenitrile 
• 20296-07-5 1-hydroxy-4-phenyl-2-butanone 
• 1192826-26-8 4-phenethyl-1,3-dioxolane 
• 1189195-95-6 C₁₂H₁₅NO₅S 
• 1300732-48-2 C₁₂H₁₇NO₂S 
• 501-52-0 3-Phenylpropionic acid 
• 4263-93-8 2-hydroxy-4-phenylbutanoic acid 
• 1430731-63-7 (R)-(+)-2-(tert-butyldimethylsilyloxy)-4-phenylbutan-1-ol 

Relevant articles and documents

Lewis Base Catalyzed Dioxygenation of Olefins with Hypervalent Iodine Reagents

1,2-Diols are extremely useful building blocks in organic synthesis. Hypervalent iodine reagents are useful for the vicinal dihydroxylation of olefins to give 1,2-diols under metal-free conditions, but strongly acidic promoters are often required. Herein, we report a catalytic vicinal dioxygenation of olefins with hypervalent iodine reagents using Lewis bases as catalysts. The conditions are mild and compatible with various functional groups.

Iron-Catalyzed Diborylation of Unactivated Aliphatic gem-Dihalogenoalkenes: Synthesis of 1,2-Bis(boryl)alkanes

Herein, we report the first example of iron-catalyzed defluoroborylation of unactivated gem-difluoroalkenes, gem-dichloroalkenes, and gem-dibromoalkenes, providing the 1,2-bis(boryl)alkanes in moderate to good yield. This transformation has high regiosele

Site-Selective Mono-Oxidation of 1,2-Bis(boronates)

Site-selective oxidation of vicinal bis(boronates) is accomplished through the use of trimethylamine N-oxide in 1-butanol solvent. The reaction occurs with good efficiency and selectivity across a range of substrates, providing 2-hydro-1-boronic esters which are shown to be versatile intermediates in the synthesis of chiral building blocks.