144499-26-3

Basic information

• Product Name: 2-Quinoxalinol(9CI)
• Synonyms: 2-Quinoxalinol(9CI)
• CAS NO: 144499-26-3
• Molecular Formula: C8H6N2O
• Molecular Weight: 146.15
• Product Categories: QUINOXALINE
• Mol File: 144499-26-3.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• Density: 1.347
• CAS DataBase Reference: 2-Quinoxalinol(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Quinoxalinol(9CI)(144499-26-3)
• EPA Substance Registry System: 2-Quinoxalinol(9CI)(144499-26-3)

Safety Data

• Hazardous Substances Data: 144499-26-3(Hazardous Substances Data)

Usage

General Description

2-Quinoxalinol (9CI) is a chemical compound with the molecular formula C8H6N2O. It is a heterocyclic compound with a quinoxaline ring and a hydroxyl group attached to the carbon atoms. 2-Quinoxalinol is used in the production of pharmaceuticals and agrochemicals and has potential applications in organic synthesis. It may also have biological activities, such as antifungal and antibacterial properties, making it a subject of interest for further research and development. 2-Quinoxalinol is a versatile compound with various potential uses in different fields, and its properties and applications continue to be explored and studied.

Upstream product

• 13593-03-8 quinalphos 
• 95-54-5 1,2-diamino-benzene 
• 2423-66-7 quinoxaline 1,4-di-N-oxide 
• 60-29-7 diethyl ether 
• 57987-56-1 1,2-diethoxy-1,2-dichloro-ethane 
• 1448-87-9 2-chloroquinoxaline 
• 67-63-0 isopropyl alcohol 
• 64-17-5 ethanol 
• 67-56-1 methanol 
• 109745-70-2 methyl glyoxylate methyl hemi-acetal 
• 59564-59-9 3,4-dihydro-2-hydroxyquinoxaline 
• 140-18-1 Benzyl chloroacetate 
• 4937-77-3 4-(phenylsulfonyl)-3,4-dihydroquinoxalin-2(1H)-one 
• 16622-05-2 anhydro-1-hydroxy-3-methyl-s-triazolo<4,3-a>quinoxalinium hydroxide 

Downstream Products

• 1385829-25-3 4-{4-[2-(4-(quinoxalin-2-yl)piperazin-1-yl)ethyl]phenyl}thiazol-2-amine 
• 1385829-26-4 N-methyl-4-{4-[2-(4-(quinoxalin-3-yl)piperazin-1-yl)ethyl]phenyl}thiazol-2-amine 
• 36856-91-4 2-bromo-quinoxaline 
• 933443-68-6 4-(quinoxalin-2-yloxy)-benzoic acid methyl ester 
• 875153-03-0 4-(quinoxalin-2-yloxy)-benzoic acid 
• 6479-18-1 1-methyl-2(1H)-quinoxalinone 
• 63536-44-7 1-benzyl-1,2-dihydroquinoxalin-2-one 

Relevant articles and documents

Decarboxylative Hydroxylation of Benzoic Acids

Herein, we report the first decarboxylative hydroxylation to synthesize phenols from benzoic acids at 35 °C via photoinduced ligand-to-metal charge transfer (LMCT)-enabled radical decarboxylative carbometalation. The aromatic decarboxylative hydroxylation is synthetically promising due to its mild conditions, broad substrate scope, and late-stage applications.

Multi-gram preparation of 7-nitroquinoxalin-2-amine

Methodologies to obtain quinoxaline compounds regioselectively are rarely reported in literature, thus regioselective and multi-gram methodologies to obtain these derivatives are desirable to explore the entire potential of these scaffolds for academic and/or commercial application. A facile and multi-gram methodology is described to obtain compound 7-nitroquinoxalin-2-amine using o-phenylenediamine, a cheap and readily available reactant, as starting material in a five-step procedure in good yields and high purity without further purification such as crystallization or column chromatography.

Dibenzothiophene Catabolism Proceeds via a Flavin-N5-oxide Intermediate

The dibenzothiophene catabolic pathway converts dibenzothiophene to 2-hydroxybiphenyl and sulfite. The third step of the pathway, involving the conversion of dibenzothiophene sulfone to 2-(2-hydroxyphenyl)-benzenesulfinic acid, is catalyzed by a unique flavoenzyme DszA. Mechanistic studies on this reaction suggest that the C2 hydroperoxide of dibenzothiophene sulfone reacts with flavin to form a flavin-N5-oxide. The intermediacy of the flavin-N5-oxide was confirmed by LC-MS analysis, a co-elution experiment with chemically synthesized FMN-N5-oxide and 18O2 labeling studies.