14475-59-3Relevant articles and documents
Structural control of the horizontal double fixation of oligothiophenes on gold
Tran, Truong Khoa,Ocafrain, Maitena,Karpe, Sandrine,Blanchard, Philippe,Roncali, Jean,Lenfant, Stephane,Godey, Sylvie,Vuillaume, Dominique
, p. 6237 - 6246 (2008)
Quaterthiophenes bearing one (1) or two (2) alkanethiol chains attached at the internal β-position of the outermost thiophene ring through a sulfide linkage have been synthesized. Cyclic voltammetric analysis of their electrochemical behavior in solution suggests that electrooxidation of the doubly substituted oligomer 2 leads to electrodeposition of a poly(disulfide) on the anode surface. Monolayers of 1 or 2 on gold surfaces have been investigated and characterized by cyclic voltammetry, ellipsometry, contact angle measurement, and X-ray photoelectron spectroscopy. The results of these investigations indicate that introduction of two thiol groups in the structure leads to double fixation of the oligothiophene chain with the main axis of the conjugated system oriented parallel to the surface. The effects of single versus double fixation of the quaterthiophene chain on the electrochemical properties and stability of the corresponding monolayers are discussed.
QUINOLYL-CONTAINING COMPOUND AND PHARMACEUTICAL COMPOSITION, AND USE THEREOF
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Paragraph 0145-0148, (2022/02/19)
Provided is a quinolyl-containing compound as shown in general formula (I) or (II) or a pharmaceutically acceptable salt, a solvate, an active metabolite, a polymorph, an isotopic label, or an isomer thereof, and further provided are a pharmaceutical composition comprising the compound and use of the compound and the pharmaceutical composition. The provided compound has a dual molecule function, can serve as multi -target inhibitors of novel tyrosine kinase/histone deacetylase, can simultaneously achieve the effect of two inhibitors, has excellent biological activity and pharmacokinetic properties, and has the application potential particularly in the field of treatment of tumors.
Halogenated-1-(4-mercaptobutyl)-3-methylimidazole ionic liquid, preparation method and application thereof
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Paragraph 0031; 0033; 0035, (2018/01/11)
The invention discloses a halogenated-1-(4-mercaptobutyl)-3-methylimidazole ionic liquid, a preparation method and application thereof. According to the invention, N-methylimidazole, potassium thioacetate and 1, 4-dihalobutane are adopted as the raw materials, and three steps of reactions are carried out to synthesize the target product. The method has the advantages of short reaction cycle, mild reaction conditions of the steps, simple post-treatment process, good repeatability and stability, and is suitable for popularization and application. The ionic liquid prepared by the method provided by the invention can be applied to a micro-extraction system of ionic liquid to serve as an extractant or dispersant. The ionic liquid prepared by the method provided by the invention greatly improves the fluorescence sensitivity of detection in biomacromolecule fluorescence detection, also can be used as a fluorescence probe for pesticide residue detection, and has good analytical application value.