14683-79-5

Basic information

• Product Name: Benzaldehyde, 2-methyl-, oxime
• CAS NO: 14683-79-5
• Molecular Formula: C8H9NO
• Molecular Weight: 135.166
• Mol File: 14683-79-5.mol
• Article Data: 48

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-methyl-, oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-methyl-, oxime(14683-79-5)
• EPA Substance Registry System: Benzaldehyde, 2-methyl-, oxime(14683-79-5)

Safety Data

• Hazardous Substances Data: 14683-79-5(Hazardous Substances Data)

Upstream product

• 53724-30-4 o-Methyl-dithiobenzoesaeure 
• 529-20-4 2-methylphenyl aldehyde 
• 108-88-3 toluene 
• 92114-96-0 mercury fulminate 
• 5470-11-1 hydroxylamine hydrochloride 
• 54043-60-6 1,3,5-tris(o-tolyl)-hexahydro-s-triazine 
• 95-53-4 o-toluidine 
• 64380-54-7 2-(2-methylphenyl)-1,3-dioxolane 
• 75-52-5 nitromethane 
• 22755-24-4 sodium salt of nitromethane 
• 89-95-2 2-methyl-benzyl alcohol 
• 95-46-5 2-methylphenyl bromide 
• 68-12-2 N,N-dimethyl-formamide 
• 89-93-0 ortho-methylbenzylamine 

Downstream Products

• 87-24-1 ethyl 2-methylbenzoate 
• 74467-03-1 N-hydroxy-2-methylbenzenecarboximidoyl chloride 
• 26177-23-1 1-dinitromethyl-2-methyl-benzene 
• 127459-91-0 (Z)-2-methylbenzaldoxime 
• 529-20-4 2-methylphenyl aldehyde 
• 527-85-5 o-Methylbenzamid 
• 1262209-94-8 3-(2-toluyl)-8,9-dihydrodibenzo[3,4:7,8]cycloocta[1,2-d]isoxazol-9-ol 
• 1333623-86-1 4-propyl-3-o-tolyl-1,2,4-oxadiazol-5(4H)-one 
• 1346772-12-0 (Z)-N'-hydroxy-2-methyl-N-propylbenzimidamide 
• 1399860-73-1 3-methoxy-17α-[3'-(2-methyl)phenylisoxazol-5'-yl]estra-1,3,5(10),16-tetraene 
• 16216-14-1 o-methylbenzil 
• 1398122-53-6 C₁₉H₂₀O₄ 
• 65349-23-7 3-(2-methylphenyl)-5-phenylisoxazole 

Relevant articles and documents

A catalytic regioselective procedure for the synthesis of aryl oximes in the presence of palladium nanoparticles

The synthesis of aryl oximes from aryl aldehyde derivatives was carried out using hydroxylamine hydrochloride and aluminum oxy hydroxide-supported palladium (Pd/AlO(OH) nanoparticles. The procedure is revealed via the regioselective synthesis of oxime der

Dibenzazepine-linked isoxazoles: New and potent class of α-glucosidase inhibitors

α-Glucosidase inhibition is a valid approach for controlling hyperglycemia in diabetes. In the current study, new molecules as a hybrid of isoxazole and dibenzazepine scaffolds were designed, based on their literature as antidiabetic agents. For this, a series of dibenzazepine-linked isoxazoles (33–54) was prepared using Nitrile oxide-Alkyne cycloaddition (NOAC) reaction, and evaluated for their α-glucosidase inhibitory activities to explore new hits for treatment of diabetes. Most of the compounds showed potent inhibitory potency against α-glucosidase (EC 3.2.1.20) enzyme (IC50 = 35.62 ± 1.48 to 333.30 ± 1.67 μM) using acarbose as a reference drug (IC50 = 875.75 ± 2.08 μM). Structure-activity relationship, kinetics and molecular docking studies of active isoxazoles were also determined to study enzyme-inhibitor interactions. Compounds 33, 40, 41, 46, 48–50, and 54 showed binding interactions with critical amino acid residues of α-glucosidase enzyme, such as Lys156, Ser157, Asp242, and Gln353.

A Synergic Activity of Urea/Butyl Imidazolium Ionic Liquid Supported on UiO-66-NH2 Metal–Organic Framework for Synthesis of Oximes

An efficient supported ionic liquid catalyst is designed for condensation reaction of aldehydes and ketones. The Zr-based metal–organic framework (MOF), UiO-66-NH2, was initially functionalized with N,N′-dibutyl imidazolium ionic liquid (UiO-66-NH2-ILBr–), and then urea was attached to the ionic liquid (IL) to form a task-specific IL. Bromide was exchanged with tetrafluoroborate and the catalyst exhibits excellent performance for the synthesis of oximes. The ionic liquid/urea coupling showed a synergistic effect on the efficiency of the reaction. The supported catalyst system was recycled simply by filtration and reused for five times without significant decrease in its activity. The catalyst was characterized with PXRD, FTIR, TGA, XPS, BET, FE-SEM, EDS, elemental mapping and elemental analysis (CHN). Graphic Abstract: MOF/IL/urea catalytic system was used for the synthesis of oximes[Figure not available: see fulltext.].