319-76-6 Usage
Derived from
Synthetic derivative of indole (heterocyclic aromatic organic compound)
Application in research
Selective antagonist for the serotonin 5-HT3 receptor in biochemistry and molecular biology
Potential therapeutic uses
Treatment of diseases such as schizophrenia, depression, and as an analgesic
Receptor interaction
Potent and selective inhibitor of the serotonin receptor
Importance
Valuable tool for studying the role of serotonin in various physiological and pathological conditions
Check Digit Verification of cas no
The CAS Registry Mumber 319-76-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 319-76:
(5*3)+(4*1)+(3*9)+(2*7)+(1*6)=66
66 % 10 = 6
So 319-76-6 is a valid CAS Registry Number.
319-76-6Relevant articles and documents
Nucleophilic substitution reactions on indole nucleus: Formation of (3a,8a-cis)-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indoles having a substituent at the 3a-position
Yamada, Fumio,Goto, Aya,Hasegawa, Masakazu,Kobayashi, Kensuke,Somei, Masanori
, p. 844 - 861 (2017/07/28)
Various nucleophiles, such as indole, 1,2,3-trimethoxybenzene, anisole, phenol, and pyrrole, reacted with 1-hydroxy-Nb-trifluoroacetyltryptamine under the presence of mesyl chloride to give novel series of (3a,8acis)- 1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indoles having a substituent at the 3aposition. Their structures and by-products were strictly determined.
