149108-75-8

Basic information

• Product Name: CYCLOHEXYLMETHYL 2-PYRIDYL KETONE
• Synonyms: CYCLOHEXYLMETHYL 2-PYRIDYL KETONE
• CAS NO: 149108-75-8
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.28
• Mol File: 149108-75-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 318.043°C at 760 mmHg
• Flash Point: 154.151°C
• Appearance: /
• Density: 1.034g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: CYCLOHEXYLMETHYL 2-PYRIDYL KETONE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOHEXYLMETHYL 2-PYRIDYL KETONE(149108-75-8)
• EPA Substance Registry System: CYCLOHEXYLMETHYL 2-PYRIDYL KETONE(149108-75-8)

Safety Data

• Hazardous Substances Data: 149108-75-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H17NO/c15-13(12-8-4-5-9-14-12)10-11-6-2-1-3-7-11/h4-5,8-9,11H,1-3,6-7,10H2

Upstream product

• 109-04-6 2-bromo-pyridine 
• 134560-43-3 2-cyclohexyl-N-methoxy-N-methylacetamide 
• 155392-46-4 2-cyclohexyl-1-(2-pyridyl)ethanol 
• 17624-36-1 2-pyridyllithium 
• 5292-21-7 Cyclohexylacetic acid 
• 23860-35-7 cyclohexylacetic acid chloride 
• 1121-60-4 pyridine-2-carbaldehyde 
• 2550-36-9 Cyclohexylmethyl bromide 
• 98-98-6 2-Picolinic acid 
• 1227056-27-0 2,2'-(2-cyclohexylethane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 

Downstream Products

• 149108-78-1 (R)-2-((S)-2-Cyclohexyl-1-pyridin-2-yl-ethylamino)-2-phenyl-ethanol 
• 183962-51-8 1-(S,R)-(pyridin-2-yl)-2-cyclohexylethylamine 
• 910480-83-0 4-cyclohexyl-5-pyridin-2-yl-1H-pyrrole-2-carbaldehyde 
• 910480-82-9 2-(3-cyclohexyl-1H-pyrrol-2-yl)-pyridine 
• 910480-81-8 3-cyclohexyl-4-oxo-4-pyridin-2-yl-butyraldehyde 
• 918936-53-5 2-cyclohexyl-1-pyridin-2-yl-pent-4-en-1-one 

Relevant articles and documents

Dual Functionalization of α-Monoboryl Carbanions through Deoxygenative Enolization with Carboxylic Acids

A dual functionalization of 1,1-diborylalkanes through deoxygenative enolization with carboxylic acids was developed. 1,1-Diborylalkanes were activated by MeLi to generate α-monoboryl carbanions. In situ IR spectroscopy indicated an interaction between carboxylic acid and 1,1-diborylalkane before addition of the activation reagent. Release of the active α-monoboryl carbanion from the masked form was necessary for its reaction with carboxylate to afford enolate species. Electrophilic trapping of enolate species with various electrophiles achieved dual functionalization of 1,1-diborylalkanes to afford a variety of α-mono, di-, and tri-substituted ketones.

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF CANCERS, INCLUDING HEPATOCELLULAR CARCINOMA, AND AS INHIBITORS OF HEPATITIS VIRUS REPLICATION

Pharmaceutical compositions of the invention are presented which comprise substiuted aminothiazoles derivatives. The substiuted aminothiazoles derivatives have a disease-modifying action in the treatment of diseases associated with unregulated cell growth. Such diseases include cancers such as hepatocellular carcinoma, and viral infections from a hepatitis virus.

Enantiomerically pure pyridylcycloalkylethylamines and the salts thereof and processes for preparing them

The present invention relates to new enantiomerically pure pyridylcycloalkylethylamines of formula 1a and 1b, the salts thereof as well as to methods of preparing them and their use as intermediate products. STR1