150250-33-2

Basic information

• Product Name: Tetraethyl(O-tetrahydropyranyl-propylidene)bisphosphonate, 95 %
• Synonyms: Tetraethyl(O-tetrahydropyranyl-propylidene)bisphosphonate, 95 %;Tetraethyl (O-tetrahydropyranyl-propylidene)bisphosphonate;tetraethyl (4-((tetrahydro-2H-pyran-2-yl)oxy)butane-1,1-diyl)bis(phosphonate)(WXG01806)
• CAS NO: 150250-33-2
• Molecular Formula: C₁₇H₃₆O₈P₂
• Molecular Weight: 416.385
• Mol File: 150250-33-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 526.0±50.0 °C(Predicted)
• Appearance: /
• Density: 1.13±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Tetraethyl(O-tetrahydropyranyl-propylidene)bisphosphonate, 95 %(CAS DataBase Reference)
• NIST Chemistry Reference: Tetraethyl(O-tetrahydropyranyl-propylidene)bisphosphonate, 95 %(150250-33-2)
• EPA Substance Registry System: Tetraethyl(O-tetrahydropyranyl-propylidene)bisphosphonate, 95 %(150250-33-2)

Safety Data

• Hazardous Substances Data: 150250-33-2(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 33821-94-2 3-(tetrahydro-2H-pyran-2-yloxy)propyl bromide 
• 1660-94-2 Tetraethyl methylenediphosphonate 

Downstream Products

• 136496-88-3 tetraethyl 3-carboxypropylene-1,1-bisphosphonate 
• 925684-97-5 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(4-(3-(4-(4,4-bis(diethylphosphono)butoxy)phenyl)-3-oxopropyl)-3-methylpiperazin-1-yl)-8-methoxy-4-oxoquinoline-3-carboxylic acid 
• 947537-33-9 C₆₇H₉₆N₄O₁₉P₂ 
• 925684-96-4 1-(4-(4,4-bis(diethylphosphono)butoxy)phenyl)prop-2-en-1-one 
• 150250-34-3 tetraethyl 4-hydroxybutylene-1,1-bisphosphonate 
• 90315-14-3 tetraethyl 4-aminobutylidene-1,1-bisphosphonate 

Relevant articles and documents

PHOSPHONATED RIFAMYCINS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS

The present invention relates to phosphonated Rifamycins, and methods of making and using such compounds. These compounds are useful as antibiotics for prophylaxis and/or the treatment of bone and joint infections, especially for the prophylaxis and/or treatment of osteomyelitis.

PHOSPHONATED GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS

The present invention is directed to antimicrobial compounds which have an affinity for binding bones. More particularly, the invention is directed to phosphonated derivatives of glycopeptide or lipoglycopeptide antibiotics. These compounds are useful as antibiotics for the prevention or treatment of bone and joint infections, especially for the prevention and treatment of osteomyelitis.

Linking bisphosphonates to the free amino groups in fluoroquinolones: Preparation of osteotropic prodrugs for the prevention of osteomyelitis

Osteomyelitis is an infection located in bone and a notoriously difficult disease to manage, requiring frequent and heavy doses of systemically administered antibiotics. Targeting antibiotics to the bone after systemic administration may provide both grea