150760-45-5

Basic information

• Product Name: 2-(2,2-DIMETHOXYETHYL) BENZAMINE
• Synonyms: 2-(2,2-DIMETHOXYETHYL) BENZAMINE;2-(2,2-Dimethoxyethyl)aniline;BenzenaMine,2-(2,2-diMethoxyethyl)-
• CAS NO: 150760-45-5
• Molecular Formula: C₁₀H₁₅NO₂
• Molecular Weight: 181.24
• Mol File: 150760-45-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 260.5°C at 760 mmHg
• Flash Point: 120.3°C
• Appearance: /
• Density: 1.062g/cm³
• Vapor Pressure: 0.0122mmHg at 25°C
• Refractive Index: 1.53
• PKA: 4.24±0.10(Predicted)
• CAS DataBase Reference: 2-(2,2-DIMETHOXYETHYL) BENZAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-DIMETHOXYETHYL) BENZAMINE(150760-45-5)
• EPA Substance Registry System: 2-(2,2-DIMETHOXYETHYL) BENZAMINE(150760-45-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 150760-45-5(Hazardous Substances Data)

Usage

General Description

2-(2,2-Dimethoxyethyl) benzamine, also known as DMEDA, is a chemical compound with the formula C10H15NO2. It is a colorless to pale yellow liquid with a slight amine odor, and it is commonly used as a catalyst and curing agent in various chemical reactions and processes. DMEDA is often used in the production of polymers, resins, and coatings, and it acts as a crosslinking agent in the synthesis of polyurethane and epoxy products. It is also used as a precursor for the synthesis of pharmaceuticals and other organic compounds. Additionally, it is used as a stabilizer and inhibitor in the synthesis of dyes, pigments, and other organic chemicals.

InChI:InChI=1/C10H15NO2/c1-12-10(13-2)7-8-5-3-4-6-9(8)11/h3-6,10H,7,11H2,1-2H3

Upstream product

• 32991-03-0 trans-β-dimethylamino-2-nitrostyrene 
• 20973-67-5 N,N-dimethyl-2-(2-nitrophenyl)ethenylamine 
• 7318-34-5 1-(2-nitrophenyl)-4-chloro-2-butene 
• 88-72-2 1-methyl-2-nitrobenzene 
• 1969-73-9 (2-nitrophenyl)acetaldehyde 
• 32989-69-8 trans-2-nitro-β-pyrrolidinostyrene 
• 79844-33-0 2-(2-nitrophenyl)acetaldehyde dimethyl acetal 
• 119-66-4 2-nitrobenzenediazonium chloride 

Downstream Products

• 170364-89-3 4-(indol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 201486-60-4 1-Indol-1-yl-4-(4-methoxy-phenoxy)-butan-1-ol 
• 201486-52-4 1-Indol-1-yl-4-(4-methoxy-phenoxy)-butan-1-one 
• 201486-54-6 (2,4-Dimethoxy-phenyl)-indol-1-yl-methanone 
• 201486-62-6 1-Indol-1-yl-5-phenyl-pentan-1-ol 
• 201486-55-7 (E)-1-(1H-indol-1-yl)-3-phenylprop-2-en-1-one 
• 616898-64-7 oxo-[1-(1-pyridin-2-ylmethyl-piperidin-4-yl)-1H-indol-3-yl]-oxo-acetic acid methyl ester 
• 170364-57-5 enzastaurin 
• 594827-31-3 1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1H-indole 
• 118511-81-2 1-(4-piperidinyl)-1H-indole 
• 592479-02-2 2-(2-isocyanophenyl)acetaldehyde dimethyl acetal 
• 951024-75-2 C₂₇H₂₈N₂O₇ 
• 951024-80-9 C₂₉H₃₆N₂O₉ 
• 951024-79-6 C₂₅H₃₂N₂O₇ 

Relevant articles and documents

Development of a manufacturing process for 1-(1-pyridin-2-yl methyl-piperidin-4-yl)-1H-indole: A key intermediate for protein kinase C inhibitor LY317615

This contribution describes process development leading to the production of 1-(1-pyridin-2-yl methyl-piperidin-4-yl)-1H-indole (11). The title compound 11 was produced via a Leimgruber-Batcho indole synthesis using key intermediates 2-(2,2-dimethoxyethyl

TFA-catalysed tandem double cyclisation: A one-pot, metal-free routes for novel indolo-imidazo[1,2-a]pyridine derivatives

A transition-metal free, one-pot tandem synthetic routes for novel indole and imidazo[1,2-a]pyridine derivative hybrids have been established. An efficient three-component reaction was designed with incorporation of two sequential Groebke–Blackburn–Bienay

New entry to convertible isocyanides for the Ugi reaction and its application to the stereocontrolled formal total synthesis of the proteasome inhibitor omuralide

The development of a new convertible isocyanide, indole-isocyanide, for ready access to pyroglutamic acids culminated in the formal total synthesis of the proteasome inhibitor omuralide featuring a stereocontrolled Ugi reaction. Indole-isocyanide was name