150760-45-5

Usage

Uses

Used in Polymer and Resin Production:
2-(2,2-Dimethoxyethyl) benzamine is used as a catalyst and curing agent in the production of polymers, resins, and coatings. It facilitates the curing process and enhances the properties of the final products.
Used in Polyurethane and Epoxy Synthesis:
2-(2,2-Dimethoxyethyl) benzamine is used as a crosslinking agent in the synthesis of polyurethane and epoxy products. It helps to create a network structure, improving the mechanical and chemical properties of the materials.
Used in Pharmaceutical Synthesis:
2-(2,2-Dimethoxyethyl) benzamine is used as a precursor in the synthesis of pharmaceuticals and other organic compounds. Its unique chemical structure allows for the development of new drugs and therapeutic agents.
Used in Dye and Pigment Synthesis:
2-(2,2-Dimethoxyethyl) benzamine is used as a stabilizer and inhibitor in the synthesis of dyes, pigments, and other organic chemicals. It helps to improve the stability and performance of these colorants in various applications.

InChI:InChI=1/C10H15NO2/c1-12-10(13-2)7-8-5-3-4-6-9(8)11/h3-6,10H,7,11H2,1-2H3

Upstream product

• 88-72-2 1-methyl-2-nitrobenzene 
• 119-66-4 2-nitrobenzenediazonium chloride 
• 32991-03-0 trans-β-dimethylamino-2-nitrostyrene 
• 20973-67-5 N,N-dimethyl-2-(2-nitrophenyl)ethenylamine 
• 7318-34-5 1-(2-nitrophenyl)-4-chloro-2-butene 
• 1969-73-9 (2-nitrophenyl)acetaldehyde 
• 32989-69-8 trans-2-nitro-β-pyrrolidinostyrene 
• 79844-33-0 2-(2-nitrophenyl)acetaldehyde dimethyl acetal 

Downstream Products

• 201486-53-5 1-Indol-1-yl-5-phenyl-pentan-1-one 
• 201486-48-8 N-[2-(2,2-Dimethoxy-ethyl)-phenyl]-4-(4-methoxy-phenoxy)-butyramide 
• 170365-11-4 1-(1-Benzyl-piperidin-4-yl)-1H-indole 
• 170364-89-3 4-(indol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 592478-96-1 N-[2-(2,2-dimethoxyethyl)phenyl]formamide 
• 201486-60-4 1-Indol-1-yl-4-(4-methoxy-phenoxy)-butan-1-ol 
• 201486-52-4 1-Indol-1-yl-4-(4-methoxy-phenoxy)-butan-1-one 
• 201486-54-6 (2,4-Dimethoxy-phenyl)-indol-1-yl-methanone 
• 201486-62-6 1-Indol-1-yl-5-phenyl-pentan-1-ol 
• 201486-55-7 (E)-1-(1H-indol-1-yl)-3-phenylprop-2-en-1-one 
• 616898-64-7 oxo-[1-(1-pyridin-2-ylmethyl-piperidin-4-yl)-1H-indol-3-yl]-oxo-acetic acid methyl ester 
• 170364-57-5 enzastaurin 
• 594827-31-3 1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1H-indole 
• 118511-81-2 1-(4-piperidinyl)-1H-indole 

Relevant academic research and scientific papers

Development of a manufacturing process for 1-(1-pyridin-2-yl methyl-piperidin-4-yl)-1H-indole: A key intermediate for protein kinase C inhibitor LY317615

This contribution describes process development leading to the production of 1-(1-pyridin-2-yl methyl-piperidin-4-yl)-1H-indole (11). The title compound 11 was produced via a Leimgruber-Batcho indole synthesis using key intermediates 2-(2,2-dimethoxyethyl

Application of the Cleavable Isocyanide in Efficient Approach to Pyroglutamic Acid Analogues with Potential Biological Activity

Two efficient procedures have been developed for the synthesis of pyroglutamic acid analogues 28, 29, and 34. According to the first method the Ugi (4C3C) reaction is followed by a post-transformation reaction, and the second method involves the Michael a

TFA-catalysed tandem double cyclisation: A one-pot, metal-free routes for novel indolo-imidazo[1,2-a]pyridine derivatives

A transition-metal free, one-pot tandem synthetic routes for novel indole and imidazo[1,2-a]pyridine derivative hybrids have been established. An efficient three-component reaction was designed with incorporation of two sequential Groebke–Blackburn–Bienay

COMPOUNDS USEFUL IN HIV THERAPY

The invention relates to compounds of Formula (I), (Ia), (Ib), (II) or (III), salts thereof, pharmaceutical compositions thereof, as well as therapeutic methods of treatment and prevention.

New entry to convertible isocyanides for the Ugi reaction and its application to the stereocontrolled formal total synthesis of the proteasome inhibitor omuralide

The development of a new convertible isocyanide, indole-isocyanide, for ready access to pyroglutamic acids culminated in the formal total synthesis of the proteasome inhibitor omuralide featuring a stereocontrolled Ugi reaction. Indole-isocyanide was name

Strategies for the synthesis of N-(azacycloalkyl)bisindolylmaleimides: Selective inhibitors of PKCβ

N-(Azacycloalkyl)bisindolylmaleimides 1 have been identified to be selective inhibitors of PKCβ. This manuscript will describe the synthetic approaches employed to prepare this class of compounds that resulted in development of efficient methods for prepa

Synthesis of 3-methoxyquinolines via cyclization of 1-isocyano-2-(2-lithio-2-methoxyethenyl)benzenes

2-(2-Isocyanophenyl)acetaldehyde dimethyl acetals were treated with excess LDA to generate 1-isocyano-2-(2-lithio-2-methoxyethenyl)benzenes, which cyclized intramolecularly to afford 3-methoxyquinolines in good to excellent yields.

2-(2-aminophenyl)-acetaldehyde dimethyl acetal: A novel reagent for the protection of carboxylic acids

The synthesis and use of 2-(2-aminophenyl)-acetaldehyde dimethyl acetal 1 are described. The amides 2, derived from this amine and carboxylic acids, are stable under basic conditions and thus can be regarded as the protected carboxylic acids. The corresponding carboxylic acids are regenerated by conversion of 2 into indolylamides 3 by treatment with CSA and subsequent hydrolysis with LiOOH or NaOH. In addition, 3 can be easily converted to esters, amides, and aldehydes.