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1-(2,2-DiMethoxy-ethyl)-2-isocyano-benzene, also known as DIMB, is a chemical compound with the molecular formula C11H13NO3. It is an isocyanobenzene derivative characterized by its colorless oily liquid appearance and a strong, pungent odor. DIMB is highly reactive due to the presence of the isocyanate functional group and is considered toxic, necessitating careful handling to avoid skin, eye, and respiratory irritation.

592479-02-2

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592479-02-2 Usage

Uses

Used in Organic Synthesis:
1-(2,2-DiMethoxy-ethyl)-2-isocyano-benzene is used as a reactant in organic synthesis for its reactivity and versatility in forming a variety of organic compounds.
Used in Pharmaceutical Production:
DIMB is utilized as a key component in the production of pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Chemical Research:
As a reactive isocyanobenzene derivative, 1-(2,2-DiMethoxy-ethyl)-2-isocyano-benzene is also used in chemical research to study the properties and reactions of isocyanate compounds, furthering the understanding of their applications in various industries.
Used in the Production of Other Organic Compounds:
DIMB serves as a starting material or intermediate in the synthesis of other organic compounds, highlighting its importance in the broader scope of organic chemistry.
Safety Precautions:
Given its toxicity, 1-(2,2-DiMethoxy-ethyl)-2-isocyano-benzene requires proper safety measures during handling, including the use of personal protective equipment and working in well-ventilated areas to minimize exposure risks.

Check Digit Verification of cas no

The CAS Registry Mumber 592479-02-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,2,4,7 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 592479-02:
(8*5)+(7*9)+(6*2)+(5*4)+(4*7)+(3*9)+(2*0)+(1*2)=192
192 % 10 = 2
So 592479-02-2 is a valid CAS Registry Number.

592479-02-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2-isocyanophenyl)acetaldehyde dimethyl acetal

1.2 Other means of identification

Product number -
Other names o-(2,2-dimethoxyethyl)phenyl isocyanide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:592479-02-2 SDS

592479-02-2Relevant academic research and scientific papers

COMPOUNDS USEFUL IN HIV THERAPY

-

, (2020/06/19)

The invention relates to compounds of Formula (I), (Ia), (Ib), (II) or (III), salts thereof, pharmaceutical compositions thereof, as well as therapeutic methods of treatment and prevention.

TFA-catalysed tandem double cyclisation: A one-pot, metal-free routes for novel indolo-imidazo[1,2-a]pyridine derivatives

Ganesher, Asha,Panda, Gautam

, (2019/11/11)

A transition-metal free, one-pot tandem synthetic routes for novel indole and imidazo[1,2-a]pyridine derivative hybrids have been established. An efficient three-component reaction was designed with incorporation of two sequential Groebke–Blackburn–Bienay

Application of the Cleavable Isocyanide in Efficient Approach to Pyroglutamic Acid Analogues with Potential Biological Activity

Jassem,Al-Ajely,Almashal,Chen

, p. 2562 - 2570 (2020/02/25)

Two efficient procedures have been developed for the synthesis of pyroglutamic acid analogues 28, 29, and 34. According to the first method the Ugi (4C3C) reaction is followed by a post-transformation reaction, and the second method involves the Michael a

New entry to convertible isocyanides for the Ugi reaction and its application to the stereocontrolled formal total synthesis of the proteasome inhibitor omuralide

Gilley, Cynthia B.,Buller, Matthew J.,Kobayashi, Yoshihisa

, p. 3631 - 3634 (2008/02/12)

The development of a new convertible isocyanide, indole-isocyanide, for ready access to pyroglutamic acids culminated in the formal total synthesis of the proteasome inhibitor omuralide featuring a stereocontrolled Ugi reaction. Indole-isocyanide was name

Synthesis of 3-methoxyquinolines via cyclization of 1-isocyano-2-(2-lithio-2-methoxyethenyl)benzenes

Kobayashi, Kazuhiro,Yoneda, Keiichi,Mizumoto, Tatsuya,Umakoshi, Hironobu,Morikawa, Osamu,Konishi, Hisatoshi

, p. 4733 - 4736 (2007/10/03)

2-(2-Isocyanophenyl)acetaldehyde dimethyl acetals were treated with excess LDA to generate 1-isocyano-2-(2-lithio-2-methoxyethenyl)benzenes, which cyclized intramolecularly to afford 3-methoxyquinolines in good to excellent yields.

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