15097-49-1

Basic information

• Product Name: 1-(TRIMETHYLSILYL)PYRROLIDINE
• Synonyms: N-(TRIMETHYLSILYL)PYRROLIDINE;TRIMETHYLSILYLPYRROLIDINE;1-(TRIMETHYLSILYL)PYRROLIDINE;1-(trimethylsilyl)-pyrrolidin;Pyrrolidine,1-(trimethylsilyl)-;1-(TRIMETHYLSILYL)PYRROLIDINE 97+%;1-trimethylsilylpyrrolidine,95%;Trimethyl(pyrrolizino)silane
• CAS NO: 15097-49-1
• Molecular Formula: C₇H₁₇NSi
• Molecular Weight: 143.3
• EINECS: 239-149-3
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Pyrrolidines
• Mol File: 15097-49-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 139-140 °C(lit.)
• Flash Point: 40 °F
• Appearance: /
• Density: 0.821 g/mL at 25 °C(lit.)
• Vapor Pressure: 7.98mmHg at 25°C
• Refractive Index: n20/D 1.433(lit.)
• BRN: 1304636
• CAS DataBase Reference: 1-(TRIMETHYLSILYL)PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(TRIMETHYLSILYL)PYRROLIDINE(15097-49-1)
• EPA Substance Registry System: 1-(TRIMETHYLSILYL)PYRROLIDINE(15097-49-1)

Safety Data

• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 16-26-36/37/39-45
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 3
• F: 10-21
• HazardClass: 3.1
• PackingGroup: II
• Hazardous Substances Data: 15097-49-1(Hazardous Substances Data)

Usage

Uses

1-(Trimethylsilyl)pyrrolidine (N-trimethylsilyl pyrrolidine) has been used in:ring opening reaction of L-serine β-lactone to yield corresponding 5-amino-L-alanine derivativesthe preparation of iminium triflate salts

InChI:InChI=1/C7H17NSi/c1-9(2,3)8-6-4-5-7-8/h4-7H2,1-3H3

Upstream product

• 123-75-1 pyrrolidine 
• 75-77-4 chloro-trimethyl-silane 
• 10416-59-8 N,O-bis-(trimethylsilyl)-acetamide 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 110-52-1 1,4-dibromo-butane 
• 1070-89-9 sodium hexamethyldisilazane 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 32552-28-6 2-phenyl-6-pyrrolidin-1-yl-[1,3,5]oxadiazin-4-one 
• 2456-81-7 4-pyrrolidin-1-ylpyridine 
• 103408-07-7 N-(phenylseleno)pyrrolidine 
• 93516-10-0 C₁₇H₂₄N₂ 
• 497070-73-2 3-oxo-3-(pyrrolidin-1-yl)propionic acid 
• 7137-84-0 1,3-dimethyl-2-pyrrolidin-1-yl-1,3,2-diazaphospholidine 
• 1040402-61-6 N-p-tosyl-2-(pyrrolidin-1-yl)benzhydrylamine 
• 10282-30-1 4-pyrrolidin-1-yl-benzonitrile 
• 10220-22-1 1-(4-nitro-phenyl)-pyrrolidine 

Relevant articles and documents

Palladium and nickel complexes of (P,N)-ligands based on quinolines: Catalytic activity for polymerization and oligomerization

Four (P,N)-ligands (1-4) with different steric and electronic properties were synthesized. They were used to prepare the monocationic palladium complexes [Pd(P,N)(CH3)(NCCH3)](PF6) (9-12). The structures of the newly prepared ligand 3 and the neutral palladium complex [Pd(P,N)(CH3)Cl] (10) were analysed by X-ray. The catalytic activity of the palladium complexes toward the copolymerization of styrene and ethylene with CO was low or non-existent. The nickel complexes [Ni(P,N)(1-naphthyl)Cl] (13-16), modified with the ligands 1-4, were prepared and their catalytic activity toward ethylene oligomerization was studied. They showed high activity at ambient temperature and low ethylene pressure (1-12 bar) in the presence of MAO.

An Alumino-Mannich Reaction of Organoaluminum Reagents, Silylated Amines, and Aldehydes

A multi-component coupling using organoaluminum reagents, silylated amines, and aldehydes results in the formation of tertiary amines. Both alkenyl- and alkylaluminum reagents undergo reaction with iminium ion substrates for which the corresponding Petasis borono-Mannich reactions are unsuccessful.

Deoxofluorination reactions using N,N-disubstituted aminodifluorosulfinium tetrafluoroborate salts

The synthesis of N,N-disubstituted aminodifluorosulfinium tetrafluoroborate salts is reported, and their behavior as deoxofluorinating agent was evaluated. The deoxofluorination reactions were performed using a primary alcohol, a secondary alcohol and a ketone. Results show that subtle modification of the structure of the reagents can noticeably affect the reactivity and the selectivity in deoxofluorination reactions.