151-00-8 Usage
Description
Isobutyraldehyde oxime, also known as 2-methylpropanal oxime, is a colorless to pale yellow liquid with a pungent odor and is classified as an aldehyde oxime. It is soluble in water and organic solvents and is commonly used as a reagent in organic synthesis. This versatile chemical compound is valuable in various industries due to its potential applications in the production of pesticides, pharmaceuticals, and other organic chemicals, as well as its potential as a corrosion inhibitor and a precursor for the synthesis of other compounds.
Uses
Used in Organic Synthesis:
Isobutyraldehyde oxime is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, contributing to the formation of a wide range of organic compounds.
Used in Pesticide Production:
Isobutyraldehyde oxime is used as a key intermediate in the production of pesticides, where it plays a crucial role in the synthesis of active ingredients that help control and manage pests in agriculture.
Used in Pharmaceutical Industry:
Isobutyraldehyde oxime is used as a building block in the synthesis of pharmaceuticals, contributing to the development of new drugs and medications that address various health conditions.
Used in Corrosion Inhibition:
Isobutyraldehyde oxime has been studied for its potential as a corrosion inhibitor, where it can be used to protect metal surfaces from corrosion, extending the lifespan of equipment and structures in various industries.
Used as a Precursor for Synthesis of Other Compounds:
Isobutyraldehyde oxime serves as a versatile precursor in the synthesis of other compounds, enabling the creation of new chemical entities with potential applications in various fields, including materials science, chemical research, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 151-00-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,5 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 151-00:
(5*1)+(4*5)+(3*1)+(2*0)+(1*0)=28
28 % 10 = 8
So 151-00-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H9NO/c1-4(2)3-5-6/h3-4,6H,1-2H3/b5-3+
151-00-8Relevant articles and documents
Hine et al.
, p. 5186,5190, 5193 (1970)
Process development and multikilogram syntheses of XL228 utilizing a regioselective isoxazole formation and a selective SNAr reaction to a pyrimidine core
Guz, Nathan R.,Leuser, Helena,Goldman, Erick
, p. 1066 - 1073 (2013)
Route scouting, process development, and multikilogram syntheses of an IGF-1R/Src/Bcr-Abl inihibitor are reported. Key aspects of the developed route are a regioselective [3 + 2] isoxazole formation on a pyrimidine core and a selective SNAr addition of an aryl amine to a symmetrical dichloro substituted pyrimidine. The route contains six synthetic steps and was demonstrated twice on scale, delivering 4.6 and 11.2 kg (25% and 16% overall yield), for Phase I clinical studies.
COMPOUNS, COMPOSITIONS AND METHODS OF USE
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Page/Page column 171, (2018/07/29)
Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.
An Efficient One–pot Procedure for the Direct Preparation of 4,5-Dihydroisoxazoles from Amides
Slagbrand, Tove,Kervefors, Gabriella,Tinnis, Fredrik,Adolfsson, Hans
supporting information, p. 1990 - 1995 (2017/06/09)
A Mo(CO)6 (molybdenumhexacarbonyl) catalyzed reductive functionalization of amides to afford 5-amino substituted 4,5-dihydroisoxazoles is presented. The reduction of amides generates reactive enamines, which upon the addition of hydroximinoyl chlorides and base undergoes a 1,3-dipolar cycloaddition reaction that gives access to the desired heterocyclic compounds. The transformation of amides is highly chemoselective and tolerates functional groups such as nitro, nitriles, esters, and ketones. Furthermore, a versatile scope of 4,5-dihydroisoxazoles derived from a variety of hydroximinoyl chlorides and amides is demonstrated. (Figure presented.).
