151910-10-0

Basic information

• Product Name: (1S,2R)-(E)-methyl 1-carbonyl>amino>-2-phenylcyclopropane-1-carboxylate
• Synonyms: (1S,2R)-(E)-methyl 1-carbonyl>amino>-2-phenylcyclopropane-1-carboxylate
• CAS NO: 151910-10-0
• Molecular Weight: 291.347
• Mol File: 151910-10-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1S,2R)-(E)-methyl 1-carbonyl>amino>-2-phenylcyclopropane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-(E)-methyl 1-carbonyl>amino>-2-phenylcyclopropane-1-carboxylate(151910-10-0)
• EPA Substance Registry System: (1S,2R)-(E)-methyl 1-carbonyl>amino>-2-phenylcyclopropane-1-carboxylate(151910-10-0)

Safety Data

• Hazardous Substances Data: 151910-10-0(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 123806-65-5 methyl (1S,2R)-1-amino-2-phenylcyclopropanecarboxylate 
• 180322-87-6 1-(methoxycarbonyl)-2-phenylcyclopropanecarboxylic acid 
• 75-65-0 tert-butyl alcohol 
• 151843-15-1 (1S,2R,1'S,2'R)-Methyl 1--2-phenylcyclopropane-1-carboxylate 
• 151843-16-2 (1S,2R)-2-Phenyl-1-{[1-phenyl-meth-(E)-ylidene]-amino}-cyclopropanecarboxylic acid methyl ester 
• 72397-56-9 (2R)-dimethyl 2-phenylcyclopropane-1,1-dicarboxylate 
• 180322-84-3 monomethyl (1S,2R)-2-phenylcyclopropane-1,1-dicarboxylate 

Downstream Products

• 151910-11-1 (1S,2R)-1--2-phenylcyclopropane-1-carboxylic acid 
• 86087-21-0 (1S,2R)-(E)-(+)-1-amino-2-phenyl-1-cyclopropane-1-carboxylic acid hydrochloride 

Relevant articles and documents

Preparation of both enantiomers of cyclopropane derivatives from the reaction of vinyl selenones with di-(-)-bornyl malonate

The reaction of vinyl selenones with di-(-)-bornyl malonate and sodium hydride occurred with low diastereoselectivity and afforded a mixture of two diastereomeric cyclopropane derivatives in comparable yields. These, however, could be easily separated by chromatography. Removal of the bornyl group afforded highly enantiomerically enriched cyclopropanes. An example of the simple conversions of these cyclopropanes into useful cyclopropane α-amino acids is also illustrated. The syntheses of several vinyl selenides and selenones are also described.

Asymmetric Synthesis of (1S,2R)-(+)-2-Phenyl-1-Aminocyclopropane-1-Carboxylic Acid

-