15236-11-0Relevant academic research and scientific papers
Enantioselective Synthesis of Isoflavanones by Catalytic Dynamic Kinetic Resolution
Qin, Tao,Metz, Peter
, p. 2981 - 2984 (2017/06/07)
A ruthenium-catalyzed asymmetric transfer hydrogenation of racemic isoflavanones with dynamic kinetic resolution yields virtually enantiopure isoflavanols as single diastereomers. Subsequent oxidation gives rise to isoflavanones in high enantiomeric purit
Benzoxazepine derivatives as selective estrogen receptor modulators
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Page/Page column 6, (2008/06/13)
The present invention is directed to novel benzoxazepine derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and diseases mediated by an estrogen receptor.
A simple one-pot synthesis of isoflavanones
Valenti, Piero,Belluti, Federica,Rampa, Angela,Bisi, Alessandra
, p. 3895 - 3899 (2007/10/03)
A new simple one-pot synthesis of isoflavanones 2 by reaction of benzyl 2-hydroxyphenylketones 1 with bis(dimethylamino)methane in boiling ethanol is described.
Organolead-mediated Arylation of Allyl β-Ketoesters: A Selective Synthesis of Isoflavanones and Isoflavones
Donnelly, Dervilla M.,Finet, Jean-Pierre,Rattigan, Bernard A.
, p. 1729 - 1736 (2007/10/02)
Arylation of A-ring substituted and unsabstituted 3-allyloxycarbonylchroman-4-ones with aryllead(IV) triacetates followed by selective catalytic deallyloxycarbonylation affords isoflavanones or isoflavones in high overall yields.The highest yield in the arylation step was observed in the reaction of 5,7-dimethoxychroman-4-one with the more hindered 2,4,6-trimethoxyphenyllead triacetate.
A New General Synthesis of Hydroxy- and Methoxy-isoflavones
Jain, Amolak C.,Mehta, Anita
, p. 215 - 220 (2007/10/02)
A new general synthesis of hydroxy- (5e-h) and methoxy- (5e-d) isoflavones has been accomplished in overall yields of 47-73percent from the corresponding 2-hydroxydeoxybenzoins (1a-h).The first step involves reaction with appropriate amounts of ethoxymeth
Hydroxymethylation Studies of o-Hydroxyphenyl Benzyl Ketones with and without the use of Phase Transfer Catalyst: A Novel Synthesis of Isoflavanones
Jain, P. K.,Makrandi, J. K.,Grover, S. K.
, p. 51 - 58 (2007/10/02)
o-Hydroxyphenyl benzyl ketones, having a resorcinol unit in ring-A, on treatment with formalin in chloroform-aq. potassium carbonate biphase system give the corresponding α-hydroxymethyl derivatives.This reaction when carried out in the presence of a phas
A Convenient Phase Transfer Catalysed Synthesis of Isoflavanones
Singh, Harcharan,Jain, P. K.,Makrandi, J. K.,Grover, S. K.
, p. 547 - 548 (2007/10/02)
o-Hydroxyphenyl benzyl ketones (1, 4, 6, 8, 10, 12) on treatment with diiodomethane under phase transfer catalysed conditions in the presence of n-tetrabutylammonium iodide and sodium thiosulphate have been found to undergo smooth conversion into the corresponding isoflavanones (2, 5, 7, 9, 11, 13) in good yields (60-70percent).
