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Usage

Uses

Used in Adhesives Industry:
4,4'-oxybis(benzene-1,2-diamine) is used as a key component in the production of adhesives for its high thermal stability and mechanical properties, which contribute to the adhesive's performance and durability.
Used in Coatings Industry:
In the coatings industry, 4,4'-oxybis(benzene-1,2-diamine) is utilized as a crucial ingredient in the formulation of coatings due to its resistance to chemicals and ability to enhance the overall quality and longevity of the coating.
Used in Electrical Insulating Materials Industry:
4,4'-oxybis(benzene-1,2-diamine) is employed as an essential material in the manufacturing of electrical insulating materials, leveraging its high thermal stability and resistance to chemicals to ensure the safety and reliability of electrical systems.
Used in Polyurethane and Epoxy Resins Production:
4,4'-oxybis(benzene-1,2-diamine) is used as a raw material in the production of polyurethane and epoxy resins, which are widely used in various industries due to their versatility, durability, and performance characteristics.
Note: When handling 4,4'-oxybis(benzene-1,2-diamine), it is important to take proper precautionary measures as exposure to this chemical may cause skin and eye irritation, and it is considered toxic if swallowed or inhaled.

Upstream product

• 3273-78-7 4-(4-amino-3-nitrophenoxy)-2-nitrophenylamine 
• 101-63-3 bis(4-nitrophenyl)ether 
• 100-02-7 4-nitro-phenol 
• 824-78-2 4-nitrophenol sodium salt 
• 100-00-5 4-chlorobenzonitrile 
• 101-80-4 4,4'-oxydiphenylene diamine 
• 15267-98-8 sodium 4-aminophenolate 
• 3070-87-9 N-[4-(4-acetylamino-3-nitrophenoxy)-2-nitrophenyl]acetamide 
• 3070-86-8 N-[4-(4-acetylaminophenoxy)phenyl]acetamide 
• 6149-33-3 4-(4-nitrophenoxy)aniline 
• 103-90-2 4-acetaminophenol 
• 2687-40-3 4-nitrophenyl 4'-acetamidophenyl ether 
• 2687-41-4 N-[4-(4-aminophenoxy)phenyl]acetamide 

Downstream Products

• 117255-27-3 6,6'-bis[2-phenyl-3-(p-hydroxyphenyl)quinoxaline] ether 
• 64946-35-6 4,4'-(3,3'-diphenyl-7,7'-oxy-di-quinoxalin-2-yl)-bis-aniline 
• 863134-81-0 N,N',N'',N'''-tetra-salicylidene-3,3',4,4'-tetraaminodiphenyl ether 
• 894734-47-5 5,5'-oxy-bis[2-(4'-methoxyphenyl)-1H-benzimidazole] 
• 1403460-70-7 5,5'-oxy-bis[2-(3',5'-dimethoxyphenyl)-1H-benzimidazole] 
• 1403460-71-8 5,5'-oxy-bis[2-(3',4',5'-trimethoxyphenyl)-1H-benzimidazole] 
• 1403460-72-9 5,5'-oxy-bis[2-(3'-methoxy-4'-hydroxyphenyl)-1H-benzimidazole] 
• 73672-91-0 2,2'-diphenyl-5,5'-bisbenzimidazolyl ether 
• 1403460-73-0 5,5'-oxy-bis[2-(4'-bromophenyl)-1H-benzimidazole] 
• 1403460-74-1 5,5'-oxy-bis[2-(2',4'-dichlorophenyl)-1H-benzimidazole] 
• 1403460-75-2 5,5'-oxy-bis[2-(4'-fluorophenyl)-1H-benzimidazole] 
• 4612-29-7 5,5'-oxy-bis(2,3-dihydro-2-phenyl-1H-1,3,2-benzo diaza borolane) 

Relevant academic research and scientific papers

Design of novel bis-benzimidazole derivatives as DNA minor groove binding agents

A new series of bis-benzimidazole derivatives were designed and synthesized. In vitro cytotoxicity evaluation showed that these compounds exhibited high activity against the selected tumor cells. Among them, compound 9 owned the best potential, its IC50 values being 5.95 μmol/L (mononuclear tumor cell line (U937)) and 5.58 μmol/L (cervical cancer cell (HeLa)). Fluorescence and UV-vis studies showed that compound 9 could bind into the minor groove of DNA.

Newly synthesized bis-benzimidazole derivatives exerting anti-tumor activity through induction of apoptosis and autophagy

In this study, a new series of bis-benzimidazole derivatives were designed and synthesized. Most of these new compounds showed significant anti-tumor activity in vitro compared to Hoechst 33258. Among them, the most potent compound 8 had the IC50/su

Synthesis and structure of Di[methoxy(ethoxy)carbonylamino-1H-benzimidazol- 5-yl] ethers

A procedure was developed for preparing di[methoxy(ethoxy)carbonylamino-1H- benzimidazol-5-yl] ethers by the reaction of methyl or ethyl chloroformate with sodium cyanamide, followed by the reaction of the resulting methyl or ethyl cyanocarbamate with 4-(3,4-diaminophenoxy)-1,2-phenylenediamine in acidic solution. 2005 Pleiades Publishing, Inc.

Synthesis and Anthelmintic Activity of Bisbenzimidazole-2-carbamates

The synthesis of bisbenzimidazole-2-carbamates (1-6) linked directly or by a one-atom bridge (CH2, CO, O, SO2, or S) at the 5 positions is described.Compound (4) shows interesting anthelmintic activity.

Synthesis and Anthelmintic Activity of 2-Substituted 5(6)-(5-Benzimidazolyloxy)- and 5(6)-Aryloxybenzimidazoles

A number of diaryl oxides (12-17 and 22-35) and 2,2'-disubstituted-5,5'-dibenzimidazolyl oxides (18-21) have been synthesized starting from 4-nitrophenol and 4-acetaminophenol respectively.All the compounds have been evaluated for their anthelmintic activity against Ancylostoma ceylanicum in hamsters, Nippostrongylus brasiliensis and Hymenolepsis nana in rats and Syphacia obvelata in mice.The results show that compounds 18, 19 and 33 remove 100percent of A. ceylanicum and H. nana at a single oral dose of 12.5-250 mg/kg.Compound 18 is also effective against N. brasiliensis in rats and S. obvelata in mice.

Anionic naphthalene thioureido-diphenyloxides

Oxybis-phenylbis-thioureylene tetranaphthalenepoly-sulfonic acid salts, useful as complement inhibitors, and the process for their preparation.