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4-hydroxy-2,3,6-trimethoxy-5H-benzo[7]annulen-5-one is a complex organic compound with the molecular formula C15H16O5. It is a derivative of benzo[7]annulen-5-one, which is a type of annulenone, a class of organic compounds with a seven-membered ring fused to a benzene ring. The compound is characterized by the presence of a hydroxyl group at the 4-position, and three methoxy groups at the 2, 3, and 6 positions. This molecule is of interest in the field of organic chemistry, particularly in the synthesis of natural products and pharmaceuticals, due to its unique structure and potential biological activities.

15795-64-9

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15795-64-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 15795-64-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,7,9 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 15795-64:
(7*1)+(6*5)+(5*7)+(4*9)+(3*5)+(2*6)+(1*4)=139
139 % 10 = 9
So 15795-64-9 is a valid CAS Registry Number.

15795-64-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxy-2,3,6-trimethoxybenzo[7]annulen-5-one

1.2 Other means of identification

Product number -
Other names T0501-3341

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15795-64-9 SDS

15795-64-9Relevant academic research and scientific papers

ANTAGONISTS OF THE TOLL-LIKE RECEPTOR 1/2 COMPLEX

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Page/Page column 18; 19; 20; 21, (2014/02/16)

Provided are compounds, compositions and methods for treating Toll-like receptor 1/2 complex (TLRI/2) related inflammatory disorders. Small molecules, based on the benzotropolone scaffold, capable of influencing downstream signaling are dislcosed as well as methods of making and modifying these molecules. Also provided are methods for treating a subject for a clinical condition associated with Toll? like receptor complex 1/2 activation, comprising administering to the subject an effective amount of a benzotropolone compound.

Discovery of small-molecule inhibitors of the TLR1/TLR2 complex

Cheng, Kui,Wang, Xiaohui,Zhang, Shuting,Yin, Hang

supporting information, p. 12246 - 12249 (2013/02/23)

An important regulator of innate immunity, the protein complex of Toll-like receptors 1 and 2 (TLR1/TLR2) provides an attractive target for the treatment of various immune disorders. The novel compound CU-CPT22 can compete with the binding of the specific lipoprotein ligand to TLR1/TLR2 (see picture) with high inhibitory activity and specificity. Repression of downstream signaling from TNF-α and IL-1β was also observed. Copyright

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