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Usage

Uses

Used in Pharmaceutical Industry:
(2-methyl-3-phenyloxiran-2-yl)(phenyl)methanone is used as an intermediate in the synthesis of various pharmaceutical agents. Its unique structure and properties make it a valuable component in the development of new drugs.
Used in Antibacterial Applications:
(2-methyl-3-phenyloxiran-2-yl)(phenyl)methanone is studied for its potential antibacterial properties, which could be utilized in the development of new antibiotics to combat resistant bacteria.
Used in Anti-inflammatory Applications:
(2-methyl-3-phenyloxiran-2-yl)(phenyl)methanone is also studied for its potential anti-inflammatory properties, which could be applied in the development of new treatments for inflammatory conditions.
It is important to handle and use (2-methyl-3-phenyloxiran-2-yl)(phenyl)methanone with caution and in accordance with safety protocols due to its strong odor and potential biological activities.

Upstream product

• 14182-01-5 (2E)-2-methyl-1,3-diphenylprop-2-en-1-one 
• 2114-03-6 2,2-dibromo-1-phenylpropan-1-one 
• 100-52-7 benzaldehyde 
• 132-75-2 naphthalen-1-ylacetonitrile 
• 93-55-0 1-phenyl-propan-1-one 

Downstream Products

• 71908-02-6 (2SR,3RS)-3-hydroxy-2-methyl-1,3-diphenylpropan-1-one 
• 71908-03-7 (2SR,3RS)-2-methyl-1,3-diphenyl-3-hydroxypropan-1-one 
• 181695-72-7 valdecoxib 
• 37928-17-9 5-methyl-3,4-diphenyl isoxazole 
• 13148-19-1 1,2-diphenyl(butane-1,3-dione) 
• 198470-84-7 parecoxib 
• 144601-69-4 3-hydroxy-1,2-diphenyl-but-2-en-1-one 

Relevant academic research and scientific papers

Stereodivergent Access to Enantioenriched Epoxy Alcohols with Three Stereogenic Centers via Ruthenium-Catalyzed Transfer Hydrogenation

The resolution technique of stereodivergent reaction on racemic mixtures (stereodivergent RRM) was employed for the first time in ruthenium complex catalyzed transfer hydrogenation of racemic epoxy ketones, providing a new and very simple method that allows access to enantioenriched epoxy alcohols with three stereogenic centers in a one-step fashion. The protocol features simple reaction conditions, practical operation, ability to scale up, and broad group tolerance.

Visible-light-induced photoreductive generation of radicals from epoxides and aziridines

It's a trap! Both epoxides and aziridines substituted by an aryl ketone can be reduced efficiently using visible-light photoredox catalysts. The radicals generated were trapped by allyl sulfones, and formed α-branched β-hydroxy or amino derivatives with high diastereocontrol (see scheme; dtbbpy=4,4′-di-tert-butyl-2,2′-bipyridine, ppy=2-phenylpyridine). Copyright

REACTIONS OF POLYHALO FUNCTIONAL COMPOUNDS WITH METALS AND ELECTROPHILIC REAGENTS. XVI. CHEMICAL BEHAVIOR OF α,α-DIBROMO KETONES IN THE REFORMATSKII REACTION

Geminal α,α-dibromo ketones react with zinc and carbonyl compounds.Depending on the structures of the reactants, the nature of the solvent, and the reaction conditions, α,β-unsaturated ketones, α,β-epoxy ketones, or α-alkyl-β-diketones or their mixtures are formed.

Reactions of Carbanions with Carbon Tetrachloride in Two-Phase Systems. Chlorinated Products as Nucleophilic and Electrophilic Intermediates

A variety of carbanions generated in the catalytic two-phase system (aqueous NaOH or K2CO3 and tetrabutylammonium bromide catalyst) react with CCl4 to form chlorinated products that can react as nucleophiles and electrophiles.Thus, chlorinated intermediates generated from arylacetonitriles and propiophenone in the presence of aldehydes and electrophilic alkenes form oxirane and cyclopropane derivatives, respectively.The chlorinated intermediates act as electrophiles toward Cl3C- giving (trichloromethyl)oxiranes (from aryl alkyl ketones), α-trichloromethyl nitriles (from phenyl(dialkylamino)acetonitriles), and benzoyldichloro enamines (from α-dialkylamino ketones).From secondary nitroalkanes both chloronitroalkanes and dinitro compounds can be produced.

STEREOSELECTIVE SYNTHESIS OF α,β-EPOXYPHENYLKETONES FROM α,α-DIBROMOPHENYLKETONES AND ALDEHYDES USING STANNOUS FLUORIDE

trans-α,β-Epoxyphenylketones are stereoselectively synthesized via aldol type intermediates under mild conditions starting from α,α-dibromophenylketones and aldehydes using stannous fluoride.