14182-01-5

Basic information

• Product Name: 2-methyl-1,3-diphenylprop-2-en-1-one
• CAS NO: 14182-01-5
• Molecular Formula: C₁₆H₁₄O
• Molecular Weight: 222.2818
• Mol File: 14182-01-5.mol
• Article Data: 49

Chemical Properties

• Boiling Point: 354.1°C at 760 mmHg
• Flash Point: 152.7°C
• Density: 1.078g/cm³
• Vapor Pressure: 3.44E-05mmHg at 25°C
• Refractive Index: 1.611
• CAS DataBase Reference: 2-methyl-1,3-diphenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-1,3-diphenylprop-2-en-1-one(14182-01-5)
• EPA Substance Registry System: 2-methyl-1,3-diphenylprop-2-en-1-one(14182-01-5)

Safety Data

• Hazardous Substances Data: 14182-01-5(Hazardous Substances Data)

Upstream product

• 81788-80-9 (R,R/S,S)-3-Brom-2-methyl-1,3-diphenyl-1-propanon 
• 81788-80-9 (R,S/S,R)-3-Brom-2-methyl-1,3-diphenyl-1-propanon 
• 93-55-0 1-phenyl-propan-1-one 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 100-51-6 benzyl alcohol 
• 7042-33-3 ethyl 2-methylcinnamate 
• 100-52-7 benzaldehyde 
• 155852-53-2 N-methoxy-N-methyl-α-methylcinnamamide 
• 591-50-4 iodobenzene 
• 2327-99-3 1-phenylpropadiene 
• 2258-42-6 formyl acetic anhydride 
• 201230-82-2 carbon monoxide 
• 98-80-6 phenylboronic acid 
• 673-32-5 1-Phenylprop-1-yne 

Downstream Products

• 117096-02-3 3,5-dimethyl-2,4-diphenyl-6-p-tolylpyridine 
• 26709-60-4 (Z)-2-methyl-1,3-diphenyl-2-propen-1-one 
• 158630-21-8 3,5-diphenyl-4-methyl-3,4-dihydro-2H-pyrrole-2,2-dicarboxylate de diethyle 
• 144601-69-4 3-hydroxy-1,2-diphenyl-but-2-en-1-one 
• 33815-55-3 (2SR,3RS)-2-methyl-3-phenyl-2,3-dihydro-1H-inden-1-one 
• 195832-99-6 (2S)-2-methyl-1,3-diphenyl-propan-1-one 
• 1408003-48-4 (Z)-5-acetoxy-4-methyl-1,3,5-triphenyl-4-penten-1-one 
• 875228-76-5 3-methyl-2,4-diphenylpyridine 

Relevant articles and documents

Novel one-pot approach to synthesis of indanones Through Sb(V)-catalyzed reaction of phenylalkynes with aldehydes

Catalytic SbF5 and the use of EtOH as an additive efficiently converted a mixture of phenylalkynes and aldehydes to indanone compounds in one pot, and the reaction stereoselectively afforded the corresponding 2,3-disubstituted indanones as a single trans-isomer.

Crossing extreme mechanistic barriers by antibody catalysis: Syn elimination to a cis olefin

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Palladium-Catalyzed Carbonylative Synthesis of α-Branched Enones from Aryl Iodides and Arylallenes

In this communication, an interesting carbonylation protocol for the preparation of α-branched enones has been established. Starting from readily available aryl iodides and allenes, with formic acid as the CO source and reductant, moderate to good yields of the desired enones were isolated. Although it is a carbonylation methodology, the use of a CO source can avoid the manipulation of CO gas directly. Notably, this procedure also presents the first example on carbonylative synthesis of α-branched enones.

Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol

One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.

Organic nitrite donor as well as preparation method and medical application thereof

The invention relates to the field of medicinal chemistry, in particular to an organic nitrite donor compound(structures shown in a general formula I and a general formula II)containing a 1nitromethyl2phenylethylene skeleton, a preparation method of the o

Chemoselective reduction of ?,￠-unsaturated carbonyl and carboxylic compounds by hydrogen iodide

The selective reduction of ?,￠-unsaturated carbonyl compounds was achieved to produce saturated carbonyl compounds with aqueous HI solution. The introduction of an aryl group at an ? or ￠ position efficiently facilitated the reduction with good yield. The reaction was applicable to compounds bearing carboxylic acids and halogen atoms. Through the investigation of the reaction mechanism, it was found that Michael-type addition of iodide occurred to produce ￠-iodo compounds followed by the reduction of C-I bond via anionic and radical paths.