159188-35-9Relevant academic research and scientific papers
Microwave-assisted rapid and straightforward synthesis of 2-aryl-4-quinolones from acylated 2′-aminoacetophenones
Ding, Derong,Li, Xin,Wang, Xin,Du, Yongli,Shen, Jingkang
, p. 6997 - 6999 (2007/10/03)
The syntheses of a diverse set of 2-aryl-4-quinolone derivatives were achieved by exposing corresponding acylated 2′-aminoacetophenones to microwave irradiation in the presence of NaOH. The microwave accelerated cyclizations were complete within 10-22 min
α-Glucosidase inhibition of 6-hydroxyflavones. Part 3: Synthesis and evaluation of 2,3,4-trihydroxybenzoyl-containing flavonoid analogs and 6-aminoflavones as α-glucosidase inhibitors
Gao, Hong,Kawabata, Jun
, p. 1661 - 1671 (2007/10/03)
The SAR studies suggested that the C-ring of baicalein (1) was not necessary for the activity, and validated the importance of 2,3,4- trihydroxybenzoyl structure of 1. Thus, a series of 2,3,4-trihydroxybenzoyl- containing flavonoid analogs were investigat
Antimitotic activity of 5-hydroxy-7-methoxy-2-phenyl-4-quinolones
Hadjeri, Mohamed,Peiller, Eva-Laure,Beney, Chantal,Deka, Nabajyoti,Lawson, Martin A.,Dumontet, Charles,Boumendjel, Ahcène
, p. 4964 - 4970 (2007/10/03)
We report the synthesis of 5-hydroxy-7-methoxy-2-phenyl-4-quinolones and their biological activity as antitumor agents. These molecules were initially evaluated for their ability to induce cell cycle arrest in the G2/M phase. Compounds that showed signifi
AN EFFICIENT SYNTHESIS OF DI-AND TRIMETHOXY-4-QUINOLONES
Toda, Jun,Fuse, Takako,Kishikawa, Etsuko,Ando, Naoko,Negishi, Rumi,et al.
, p. 2091 - 2098 (2007/10/02)
An excellent method of preparation of N-aryl-enamino esters (4) was achieved by developing N-N exchange reaction of an N-methyl-enamino ester (6) with di- and trimethoxyanilines (3).Thermolysis of 4 in xylene gave di- and trimethoxy-4-quinolones (7) in ex
