15951-41-4

Basic information

• Product Name: BIS(TRIMETHYLSILYL)DICHLOROMETHANE
• Synonyms: BIS(TRIMETHYLSILYL)DICHLOROMETHANE;DICHLOROBIS(TRIMETHYLSILYL)METHANE;Silane,1,1'-(dichloromethylene)bis[1,1,1-trimethyl-;Dichlorobis(trimethylsilyl)methane 97%;[dichloro(trimethylsilyl)methyl]-trimethylsilane
• CAS NO: 15951-41-4
• Molecular Formula: C₇H₁₈Cl₂Si₂
• Molecular Weight: 229.29
• Product Categories: Organometallic Reagents;Organosilicon;Others
• Mol File: 15951-41-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 117 °C17 mm Hg(lit.)
• Flash Point: 154 °F
• Appearance: /
• Density: 1.006 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.257mmHg at 25°C
• Refractive Index: n20/D 1.469(lit.)
• CAS DataBase Reference: BIS(TRIMETHYLSILYL)DICHLOROMETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(TRIMETHYLSILYL)DICHLOROMETHANE(15951-41-4)
• EPA Substance Registry System: BIS(TRIMETHYLSILYL)DICHLOROMETHANE(15951-41-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: No
• Hazardous Substances Data: 15951-41-4(Hazardous Substances Data)

Usage

General Description

BIS(TRIMETHYLSILYL)DICHLOROMETHANE is a chemical compound with the formula (CH3)3Si2Cl2. It is a colorless liquid that is commonly used as a reagent in organic synthesis. BIS(TRIMETHYLSILYL)DICHLOROMETHANE is known for its ability to protect and activate various functional groups in organic chemistry reactions. It is highly reactive due to the presence of silicon, and its use can lead to the formation of various derivatives that are valuable in pharmaceutical and agrochemical industries. BIS(TRIMETHYLSILYL)DICHLOROMETHANE is also used as a precursor in the production of siloxane polymers and silicon-based materials. However, it is important to handle this compound with caution, as it is toxic and can cause severe skin and eye irritation.

InChI:InChI=1/C7H18Cl2Si2/c1-10(2,3)7(8,9)11(4,5)6/h1-6H3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 67-66-3 chloroform 
• 75-09-2 dichloromethane 
• 56-23-5 tetrachloromethane 
• 5926-38-5 (dichloromethyl)trimethylsilane 

Downstream Products

• 18055-70-4 1,3-bis(4′-tolyl)-1,1,3,3-tetramethyldisiloxane 
• 125364-52-5 1-[(Chloro-bis-trimethylsilanyl-methyl)-dimethyl-silanyl]-4-methyl-benzene 
• 17937-54-1 1,1,3,3-tetramethyl-1,3-bis(4-chlorophenyl)disiloxane 
• 125364-53-6 1-Chloro-4-[(chloro-bis-trimethylsilanyl-methyl)-dimethyl-silanyl]-benzene 
• 122571-17-9 1,3-bis(4′-methoxyphenyl)-1,1,3,3-tetramethyldisiloxane 
• 125364-51-4 1-[(Chloro-bis-trimethylsilanyl-methyl)-dimethyl-silanyl]-4-methoxy-benzene 
• 2127-57-3 1,1,3,3-tetramethyl-1,3-bisdisiloxane 
• 125364-54-7 1-[(Chloro-bis-trimethylsilanyl-methyl)-dimethyl-silanyl]-3-trifluoromethyl-benzene 
• 125364-57-0 1-[(Dimethylsilanyl-bis-trimethylsilanyl-methyl)-dimethyl-silanyl]-4-methyl-benzene 
• 125364-63-8 1-Chloro-4-{[(iodo-dimethyl-silanyl)-bis-trimethylsilanyl-methyl]-dimethyl-silanyl}-benzene 
• 125364-59-2 1-Chloro-4-[(dimethylsilanyl-bis-trimethylsilanyl-methyl)-dimethyl-silanyl]-benzene 
• 125364-56-9 1-[(Dimethylsilanyl-bis-trimethylsilanyl-methyl)-dimethyl-silanyl]-4-methoxy-benzene 
• 125364-64-9 1-{[(Iodo-dimethyl-silanyl)-bis-trimethylsilanyl-methyl]-dimethyl-silanyl}-3-trifluoromethyl-benzene 
• 125364-60-5 1-[(Dimethylsilanyl-bis-trimethylsilanyl-methyl)-dimethyl-silanyl]-3-trifluoromethyl-benzene 

Relevant articles and documents

Simplified preparations of trialkylsilyl- and bis(trialkylsilyl)dihalomethanes via the deprotonation of dihalomethanes

Simple, high-yield routes to trialkylsilyl- and bis(trialkylsilyl)dihalomethanes are described. These compounds are prepared by the deprotonation of dibromomethane or dichloromethane by lithium diisopropylamide in the presence of a chlorosilane. The reactions are carried out at temperatures below - 70°C in THF/hexane solvent mixtures. After aqueous workup, the air- and water-stable products are isolated by either distillation or crystallization. Further reactions on these compounds are possible, as illustrated by one example.

Use of Sacrificial Anodes in Electrochemical Functionalization of Organic Halides

This article reviews the new possibilities in organic synthesis offered by the electroreduction of organic halides in the presence of various electrophiles using sacrificial metallic anodes.