159857-88-2

Basic information

• Product Name: N-Cbz-Phe-Lys(ε-Alloc)OH
• Synonyms: N-Cbz-Phe-Lys(ε-Alloc)OH
• CAS NO: 159857-88-2
• Molecular Weight: 511.575
• Mol File: 159857-88-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-Cbz-Phe-Lys(ε-Alloc)OH(CAS DataBase Reference)
• NIST Chemistry Reference: N-Cbz-Phe-Lys(ε-Alloc)OH(159857-88-2)
• EPA Substance Registry System: N-Cbz-Phe-Lys(ε-Alloc)OH(159857-88-2)

Safety Data

• Hazardous Substances Data: 159857-88-2(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 1161-13-3 N-Cbz-L-Phe 
• 63-91-2 L-phenylalanine 
• 56-87-1 L-lysine 
• 3397-32-8 N-(benzyloxycarbonyl)-phenylalanine-N-hydroxysuccinimide ester 
• 6298-03-9 (2S)-2-amino-6-{[(prop-2-en-1-yloxy)carbonyl]amino}hexanoic acid 

Downstream Products

• 159857-89-3 N-Cbz-Phe-Lys(ε-Alloc)-4-aminobenzyl alcohol 
• 1279111-08-8 Benzyloxycarbonyl-L-phenylalanyl-L-lysyl-PABC-deacetylcolchicine 
• 1279111-09-9 Benzyloxycarbonyl-L-phenylalanyl-L-lysyl-PABC-4-fluorodeacetylcolchicine 
• 1279111-12-4 C₅₅H₆₀FN₅O₁₃ 
• 1279111-11-3 C₅₅H₆₁N₅O₁₃ 
• 71448-16-3 Cbz-L-Phe-L-Lys-OH 
• 159857-90-6 N-Cbz-Phe-Lys(ε-Alloc)-4-aminobenzyl 4-nitrophenyl carbonate 

Relevant articles and documents

CONJUGATE COMPOUNDS

The invention relates to sphingoglycolipid analogues and peptide derivatives thereof, which are useful in treating or preventing diseases or such as those relating to infection, atopic disorders, autoimmune diseases or cancer.

Cathepsin B-sensitive dipeptide prodrugs. 1. A model study of structural requirements for efficient release of doxorubicin

A series of lysosomal protease-sensitive peptides attached to doxorubicin (DOX) was prepared as model substrates for internalizing anticancer immunoconjugates and potential antimetastasis prodrugs. Rates of cathepsin B-mediated release of free drug was measured for each, and human plasma stabilities for representative examples.