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(4-chlorophenyl)(2,4-dichloro-3-phenylquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)methanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1600565-48-7

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1600565-48-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1600565-48-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,0,0,5,6 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1600565-48:
(9*1)+(8*6)+(7*0)+(6*0)+(5*5)+(4*6)+(3*5)+(2*4)+(1*8)=137
137 % 10 = 7
So 1600565-48-7 is a valid CAS Registry Number.

1600565-48-7Relevant academic research and scientific papers

6-Substituted quinolines as RORγt inverse agonists

Barbay, J. Kent,Cummings, Maxwell D.,Abad, Marta,Castro, Glenda,Kreutter, Kevin D.,Kummer, David A.,Maharoof, Umar,Milligan, Cynthia,Nishimura, Rachel,Pierce, Joan,Schalk-Hihi, Celine,Spurlino, John,Tanis, Virginia M.,Urbanski, Maud,Venkatesan, Hariharan,Wang, Aihua,Woods, Craig,Wolin, Ronald,Xue, Xiaohua,Edwards, James P.,Fourie, Anne M.,Leonard, Kristi

, p. 5277 - 5283 (2017/10/30)

We identified 6-substituted quinolines as modulators of the retinoic acid receptor-related orphan receptor gamma t (RORγt). The synthesis of this class of RORγt modulators is reported, and optimization of the substituents at the quinoline 6-position that

PHENYL LINKED QUINOLINYL MODULATORS OF RORyt

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, (2015/04/21)

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also

PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T

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, (2015/05/05)

The present invention comprises compounds of Formula I. Formula I wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The inve

HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt

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, (2014/05/07)

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

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