1600565-77-2

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 122334-37-6 4-chloro-N-methoxy-N-methylbenzamide 
• 909365-96-4 6-bromo-4-hydroxy-3-phenylquinolin-2(1H)-one 
• 2613-89-0 phenylmalonic acid 
• 1600562-81-9 6-bromo-2,4-dichloro-3-phenylquinoline 
• 1600565-48-7 (4-chlorophenyl)(2,4-dichloro-3-phenylquinolin-6-yl)(1-methyl-1H-imidazol-5-yl)methanol 
• 124-41-4 sodium methylate 
• 76-05-1 trifluoroacetic acid 
• 103-80-0 phenylacetyl chloride 
• 52727-57-8 5-bromo-2-aminobenzoic acid methyl ester 
• 106-40-1 4-bromo-aniline 
• 452349-62-1 methyl 5-bromo-2-(2-phenylacetamido)benzoate 

Relevant academic research and scientific papers

HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.