16031-55-3

Basic information

• Product Name: Benzenemethanol, a-ethyl-4-methoxy-, acetate
• CAS NO: 16031-55-3
• Molecular Formula: C12H16O3
• Molecular Weight: 208.257
• Mol File: 16031-55-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-ethyl-4-methoxy-, acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-ethyl-4-methoxy-, acetate(16031-55-3)
• EPA Substance Registry System: Benzenemethanol, a-ethyl-4-methoxy-, acetate(16031-55-3)

Safety Data

• Hazardous Substances Data: 16031-55-3(Hazardous Substances Data)

Upstream product

• 104-46-1 anethole 
• 5349-60-0 1-(4-methoxyphenyl)-1-propanol 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 
• 121-97-1 4-Methoxypropiophenone 
• 75-36-5 acetyl chloride 
• 637-69-4 4-Methoxystyrene 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-45-0 4-n-propylanisole 
• 74-96-4 ethyl bromide 
• 14202-31-4 4-methoxybenzaldehyde-1,1-diacetate 

Downstream Products

• 104-46-1 anethole 
• 1025359-78-7 N-[1-(4-methoxyphenyl)propyl]-N-methylbenzenesulfonamide 
• 121-97-1 4-Methoxypropiophenone 
• 123-11-5 4-methoxy-benzaldehyde 
• 5349-60-0 1-(4-methoxyphenyl)-1-propanol 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 

Relevant articles and documents

Cobalt-Catalyzed Intermolecular Hydrofunctionalization of Alkenes: Evidence for a Bimetallic Pathway

A functional group tolerant cobalt-catalyzed method for the intermolecular hydrofunctionalization of alkenes with oxygen- and nitrogen-based nucleophiles is reported. This protocol features a strategic use of hypervalent iodine(III) reagents that enables a mechanistic shift from conventional cobalt-hydride catalysis. Key evidence was found supporting a unique bimetallic-mediated rate-limiting step involving two distinct cobalt(III) species, from which a new carbon-heteroatom bond is formed.

A novel synthesis of isoeugenol, [ring-(U)-14C]

A novel method for the preparation of isoeugenol, [ring-(U)-14C] is presented. Phenols and phenyl esters substituted in the para position with 1-hydroxyethyl or 1-hydroxypropyl acetate esters when treated with 1,8-diazabicyclo[5.4.0]undec-7-ene in dimethylformamide (DMF) eliminate the alkyl carboxylate function to give the unsaturated compound. The reaction fails with unsubstituted or ether substituted phenyl 1-hydroxyacetate esters.

Copper triflate/t-BuOOAc-catalyzed amidation of allylic and benzylic acetates with sulfonamides

A copper triflate/t-BuOOAc-catalyzed amidation of allylic and benzylic acetates has been developed which is suitable for the coupling of a wide variety of functionalized sulfonamide nucleophiles with acetate electrophiles. The methodology allows for the amidation of benzylic substrates which are not further activated by an additional adjacent alkene or alkyne, enabling simple allylic acetates and primary benzylic acetates to be used as reaction partners.