Tetrahedron p. 13449 - 13460 (1994)
Update date:2022-07-29
Topics:
Jespersen, Tina M.
Bols, Mikael
Sierks, Michael R.
Skrydstrup, Troels
(3R, 4R, 5R)-3,4-Dihydroxy-5-hydroxymethyl-piperidine (Isofagomine, 1) a potent β-glucosidase inhibitor was synthesised in a 6 step synthesis in an overall yield of 34percent starting from 1,6:2,3-dianhydro-4-O-benzyl-β-D-mannopyranose (7).A hydroxymethyl
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