16159-70-9

Basic information

• Product Name: BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER
• Synonyms: BOC-D-PHENYLALANINE P-NITROPHENYL ESTER;BOC-D-PHENYLALANINE-ONP;BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER;BOC-D-PHE-ONP;N-alpha-t-Butyloxycarbonyl-D-phenylalanine p-nitrophenyl ester;(R)-4-Nitrophenyl 2-((tert-butoxycarbonyl)aMino)-3-phenylpropanoate;N-[(1,1-Dimethylethoxy)carbonyl]-D-phenylalanine 4-nitrophenyl ester;Boc-D-phenylalanine 4-nitrophenyl ester99%
• CAS NO: 16159-70-9
• Molecular Formula: C₂₀H₂₂N₂O₆
• Molecular Weight: 386.4
• Product Categories: Amino Acid Derivatives;Amino Acids
• Mol File: 16159-70-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 128.0-128.5 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 558.4°C at 760 mmHg
• Flash Point: 291.5°C
• Appearance: /Solid
• Density: 1.24g/cm³
• Vapor Pressure: 1.67E-12mmHg at 25°C
• Refractive Index: 1.567
• Storage Temp.: 2-8°C
• PKA: 10.83±0.46(Predicted)
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER(16159-70-9)
• EPA Substance Registry System: BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER(16159-70-9)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 8
• Hazardous Substances Data: 16159-70-9(Hazardous Substances Data)

Usage

General Description

BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER is a chemical compound that is commonly used in the field of organic and medicinal chemistry. It is a derivative of phenylalanine, an essential amino acid, and contains a BOC (tert-butoxycarbonyl) protective group. BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER is often employed as a reagent in peptide synthesis, where it can be utilized as a building block for the creation of various peptides and proteins. Additionally, due to the presence of the nitrophenyl ester group, it may also be used as a substrate for enzyme-catalyzed hydrolysis reactions. Overall, BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER is a versatile compound with diverse applications in chemical and biochemical research.

InChI:InChI=1/C20H22N2O6/c1-20(2,3)28-19(24)21-17(13-14-7-5-4-6-8-14)18(23)27-16-11-9-15(10-12-16)22(25)26/h4-12,17H,13H2,1-3H3,(H,21,24)/t17-/m1/s1

Upstream product

• 19901-44-1 N-tert-butoxycarbonylphenylalanine p-nitrophenyl ester 

Downstream Products

• 100-02-7 4-nitro-phenol 
• 923601-68-7 (R)-dimethylsulfoxonium 2-oxo-3-(tert-butoxycarbonylamino)-4-phenylbutylide 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 19901-50-9 methyl (2R)-2-(t-butoxycarbonylamino)-3-phenylpropionate 
• 68800-28-2 (S)-2-{(S)-2-[2-(2-Amino-acetylamino)-acetylamino]-3-phenyl-propionylamino}-4-methylsulfanyl-butyric acid; hydrochloride 
• 68800-26-0 N-tert-butoxycarbonylglycylglycylphenylalanylmethionine 
• 62530-45-4 (S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-methylsulfanyl-butyric acid; hydrochloride 
• 58569-55-4 met-enkephalin 
• 59481-77-5 boc-Tyr-Gly-Gly-Phe-Met-OH 
• 84969-34-6 6-[(S)-2-((R)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methylsulfanyl-butyrylamino]-hexanoic acid methyl ester 
• 84969-35-7 6-[(S)-2-((R)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-4-methylsulfanyl-butyrylamino]-hexanoic acid 
• 77052-97-2 (3S,6R)-6-Benzyl-3-(2-methylsulfanyl-ethyl)-1,4,7-triaza-cyclotridecane-2,5,8-trione 
• 84969-45-9 6-[(S)-2-((R)-2-Amino-3-phenyl-propionylamino)-4-methylsulfanyl-butyrylamino]-hexanoic acid 
• 111258-71-0 N-Boc-D-phenylalanine-N-methylamide 

Relevant articles and documents

Enantioselective hydrolysis of amino acid esters by apomyoglobin: Perfect kinetic resolution of a phenylalanine derivative

Apoprotein of horse-heart myoglobin promoted enantioselective hydrolysis of 4-nitrophenyl esters of amino acids, which allowed nearly perfect kinetic resolution of racemic N-Boc-phenylalanine ester (Boc-Phe-ONp).