1620-52-6

Basic information

• Product Name: Pyridine, 4-[(phenylsulfonyl)methyl]-
• Synonyms: 4-(phenylsulfonylmethyl)pyridine;phenyl 4-picolyl sulfone;4-benzenesulfonylmethylpyridine;4-Benzenesulfonylmethyl-pyridine;4-((benzenesulfonyl)methyl)pyridine;4-phenylsulfonylmethylpyridine;4-(benzenesulfonylmethyl)pyridine
• CAS NO: 1620-52-6
• Molecular Formula: C12H11NO2S
• Molecular Weight: 233.28600
• Mol File: 1620-52-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 205 - 207 °C (CH2Cl2)
• CAS DataBase Reference: Pyridine, 4-[(phenylsulfonyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 4-[(phenylsulfonyl)methyl]-(1620-52-6)
• EPA Substance Registry System: Pyridine, 4-[(phenylsulfonyl)methyl]-(1620-52-6)

Safety Data

• Hazardous Substances Data: 1620-52-6(Hazardous Substances Data)

Upstream product

• 873-55-2 sodium benzenesulfonate 
• 1822-51-1 4-picolylchloride hydrochloride 
• 1120-87-2 4-bromopyridin 
• 3112-85-4 methylphenylsulfonate 
• 108-98-5 thiophenol 
• 27032-01-5 pyridinium 1-dicyanomethylide 
• 7205-98-3 chloromethyl phenyl sulfone 
• 110-86-1 pyridine 
• 147645-84-9 4-phenylsulfonylmethylpyridinium 1-dicyanomethylide 
• 71897-39-7 4-[(phenylthio)methyl]pyridine 
• 108-89-4 picoline 
• 98-09-9 benzenesulfonyl chloride 
• 121-44-8 triethylamine 
• 71-43-2 benzene 

Downstream Products

• 133756-42-0 1,2,3-Tris(4-pyridyl)cyclopropyl phenyl sulfone 
• 133756-42-0 1-(benzenesulfonyl)-1,2,3-tri(4-pyridyl)cyclopropane 
• 46780-27-2 4-Benzenesulfonylmethyl-1-methyl-pyridinium 
• 75990-93-1 (E)-4-<2-(3-bromophenyl)ethenyl>pyridine 
• 722-21-4 (E)-4-(4-methoxystyryl)pyridine 
• 718-24-1 (E)-4-(4-methylstyryl)pyridine 
• 138957-87-6 1-(benzenesulfonyl)-1,2,3-tris(4-(N-methylpyridiniumyl))cyclopropane triflate 
• 133756-43-1 3-(benzenesulfonyl)-1,2,3-tris(4-(N-methylpyridiniumyl))cyclopropene triflate 
• 133756-29-3 hexakis(4-pyridyl)benzene 
• 134460-59-6 3-(benzenesulfonyl)-1,2,3-tri(4-pyridyl)cyclopropene 
• 3285-93-6 1,4-dihydro-1-methyl-4-((benzenesulfonyl)methylene)pyridine 
• 2116-64-5 4-(2-phenylethyl)pyridine 
• 866392-94-1 benzyl dithioisonicotinate 
• 62586-62-3 4-(benzenesulfonylmethyl)pyridine N-oxide 

Relevant articles and documents

(E)-Specific direct Julia-olefination of aryl alcohols without extra reducing agents promoted by bases

An unprecedented base-promoted direct olefination of aryl alcohols with sulfones via a Julia-type reaction has been described. No extra reductants are needed for Julia reaction since alcohols work as double sources of aldehydes and the hydride. Generally high yields were given for both terminal and highly (E)-selective internal olefins.

Efficient new protocol to synthesize aromatic and heteroaromatic dithioesters

A very efficient, high yielding procedure to synthesize substituted aromatic and heteroaromatic dithioesters is described. It involves the reaction between (phenylsulfonyl)methyl (hetero)aromatic derivatives and elemental sulfur in basic medium, followed by alkylation.

Vicarious nucleophilic substitution of pyridines via their dicyanomethylide derivatives

Vicarious nucleophilic substitution of pyridinium 1-dicyanomethylides with 1-chloromethyl phenyl sulfone gave corresponding 4-substituted derivatives. The dicyanomethylene group was readily eliminated via radical reaction to afford 4-phenylsulfonylmethylp