1620-52-6Relevant academic research and scientific papers
(E)-Specific direct Julia-olefination of aryl alcohols without extra reducing agents promoted by bases
Yao, Chuan-Zhi,Li, Qiang-Qiang,Wang, Mei-Mei,Ning, Xiao-Shan,Kang, Yan-Biao
supporting information, p. 7729 - 7732 (2015/05/12)
An unprecedented base-promoted direct olefination of aryl alcohols with sulfones via a Julia-type reaction has been described. No extra reductants are needed for Julia reaction since alcohols work as double sources of aldehydes and the hydride. Generally high yields were given for both terminal and highly (E)-selective internal olefins.
Palladium-catalyzed Negishi α-arylation of alkylsulfones
Zhou, Gang,Ting, Pauline C.,Aslanian, Robert G.
experimental part, p. 939 - 941 (2010/05/18)
A general, mild catalytic system for α-monoarylation of various alkyl sulfones is described that utilizes palladium-catalyzed Negishi cross-coupling approach.
Efficient new protocol to synthesize aromatic and heteroaromatic dithioesters
Abrunhosa, Isabelle,Gulea, Mihaela,Masson, Serge
, p. 928 - 934 (2007/10/03)
A very efficient, high yielding procedure to synthesize substituted aromatic and heteroaromatic dithioesters is described. It involves the reaction between (phenylsulfonyl)methyl (hetero)aromatic derivatives and elemental sulfur in basic medium, followed by alkylation.
Vicarious nucleophilic substitution of pyridines via their dicyanomethylide derivatives
Itoh,Nagata,Okada,Ohsawa
, p. 220 - 222 (2007/10/02)
Vicarious nucleophilic substitution of pyridinium 1-dicyanomethylides with 1-chloromethyl phenyl sulfone gave corresponding 4-substituted derivatives. The dicyanomethylene group was readily eliminated via radical reaction to afford 4-phenylsulfonylmethylp
Vicarious nucleophilic substitution of pyridines and 1,2,3-triazines via their dicyanomethylide derivatives
Nagata,Itoh,Okada,Ohsawa
, p. 1644 - 1648 (2007/10/02)
Vicarious nucleophilic substitution using chloromethyl phenyl sulfone was applied to pyridinium and 1,2,3-triazinium dicyanomethylides to afford corresponding 4-substituted pyridinium and 5-substituted triazinium dicyanomethylides, respectively. They were
Synthesis of Tripyridiniumylpropenyl Anions from Tripyridiniumylcyclopropanes and -cyclopropenes
Crispino, Gerard A.,Breslow, Ronald
, p. 1849 - 1855 (2007/10/02)
The syntheses of three stable, isolatable tripyridiniumylpropenyl anions are described. 1,2,3-Tris(4-(N-methylpyridiniumyl))propenyl anion and 1-(benzenesulfonyl)-1,2,3-tris(4-(N-methylpyridiniumyl))propenyl anion were prepared by treating the corresponding cyclopropane with a base. 1,3-Bis(benzenesulfonyl)-1,2,3-tris(4-(N-methylpyridiniumyl))propenyl anion was prepared by nucleophilic attack of benzenesulfinate anion on 3-(benzenesulfonyl)-1,2,3-tris(4-(N-methylpyridiniumyl))cyclopropene.Reduction of this cyclopropene gave either 1-(benzenesulfonyl)-1,2,3-tris(4-(N-methylpyridiniumyl))propenyl anion or hexakis(4-(N-methylpyridiniumyl))benzene depending on the solvent used.
The acidities of 4-arylsulfonylmethylpyridines and N-methyl and N-benzyl 4-arylsulfonylmethylpyridinium cations in aqueous solution
Wodzinski, Stefan,Bunting, John W.
, p. 2635 - 2644 (2007/10/02)
The pKa values for the deprotonation of a series of 4-(X-phenylsulfonylmethyl)pyridines (6) (pKa = 19.89 (X = H); ρ = 3.0) were determined in aqueous dimethyl sulfoxide solutions at 25 deg C using the H0q acidit
