16347-95-8

Basic information

• Product Name: 4-Methoxyquinazoline
• Synonyms: 4-Methoxyquinazoline
• CAS NO: 16347-95-8
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.1726
• Mol File: 16347-95-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 287.1°Cat760mmHg
• Flash Point: 105.3°C
• Appearance: /
• Density: 1.195g/cm³
• Vapor Pressure: 0.00437mmHg at 25°C
• Refractive Index: 1.618
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Methoxyquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxyquinazoline(16347-95-8)
• EPA Substance Registry System: 4-Methoxyquinazoline(16347-95-8)

Safety Data

• Hazardous Substances Data: 16347-95-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8N2O/c1-12-9-7-4-2-3-5-8(7)10-6-11-9/h2-6H,1H3

Upstream product

• 186581-53-3 diazomethane 
• 491-36-1 4-Hydroxyquinazoline 
• 67-56-1 methanol 
• 50-00-0 formaldehyd 
• 1885-29-6 anthranilic acid nitrile 
• 36075-44-2 quinazolin-4-ylhydrazine 
• 107468-21-3 5-methoxy-3H-1,4-benzodiazepine 
• 99356-81-7 4-(trichloromethyl)quinazoline 
• 124-41-4 sodium methylate 
• 53902-59-3 N-(2-cyanophenyl)formamide 
• 5190-68-1 4-chloroquinazoline 

Downstream Products

• 16347-96-9 4-ethoxyquinazoline 
• 2453-94-3 1,3-dimethyl-4-oxo-3,4-dihydroquinazolin-1-ium iodide 
• 26060-03-7 4-Methoxy-2-phenylquinazoline 
• 55276-35-2 phenyl(quinazolin-4-yl)methanone 
• 13300-25-9 1.4-Dihydro-1-hydroxy-4-oxochinazolin 

Relevant articles and documents

Cu-benzotriazole-catalyzed electrophilic cyclization of N-arylimines: A methodical tandem approach to O-protected-4hydroxyquinazolines-

A remarkably efficient approach to O-protected-4-hydroxyquinazolines has been developed via the copper-benzotriazole (Cu-BtH)-catalyzed intramolecular electrophilic cyclization of N-arylimines, achieved through the reaction of 2-aminobenzonitriles and various aldehydes. the Partner Organisations 2014.

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One-pot etherification of purine nucleosides and pyrimidines

A one-pot synthesis of ethers derived from inosine, guanosine, 2′-deoxyguanosine, and pyrimidinones is described. Exposure of the heterocycle to 1H-benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and Cs2CO3/s

Thermal ring contraction of 3H-1,4-benzo- diazepines into quinazolines

The thermolysis of the 5-methoxy-(11a-c) and 5-diethylamino-3H-1,4- benzodiazepines (14a-c) resulted in a ring transformation to give the 4- methoxy-(12a-c) and 4-diethylaminoquinazolines (15a-c), respectively. The mechanism of this ring contraction is also described.