91182-00-2

Usage

InChI:InChI=1/C11H14N2O4/c1-3-12-9-6-5-8(11(14)17-4-2)7-10(9)13(15)16/h5-7,12H,3-4H2,1-2H3

Upstream product

• 5429-28-7 4-(diethylamino)benzoic acid 
• 96-99-1 4-chloro-3-nitrobenzoate 
• 16588-16-2 ethyl 4-chloro-3-nitrobenzoate 
• 75-04-7 ethylamine 
• 10287-54-4 p-N,N-diethylaminobenzoic acid ethyl ester 
• 64-17-5 ethanol 
• 2788-74-1 4-(ethylamino)-3-nitrobenzoic acid 

Downstream Products

• 202131-30-4 ethyl 3-amino-4-(ethylamino)benzoate 
• 861601-78-7 4-(ethyl-nitro-amino)-3,5-dinitro-benzoic acid ethyl ester 

Relevant academic research and scientific papers

HMOX1 inducers

The present invention is related to compounds of structure (I) as heme oxygenase 1 (HMOX 1) inducers. The present invention is also related a method of controlling the activity or the amount, or both the activity and the amount, of heme-oxygenase 1 in a mammalian subject. The definitions of the variables are provided herein.

Synthesis of some novel tetrahydronaphthalene benzimidazole derivatives

Retinoids, synthetic and natural analogues of all-trans-retinoic acid (RA), exert their biological effects with responsive elements of DNA to promote on cell differentiation and proliferation and behave as potent adipogenic hormones. Herein, we describe the synthesis of a number of novel tetrahydrotetramethylnaphthalene benzimidazole derivatives as retinoids. Analogs were prepared as depicted in Scheme 1 and 2. As is evident from both shemes, a variety of tetrahydrotetramethylnaphthalene benzimidazole derivatives have been synthesized by using an appropiate NaHSO3 addiction product.