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167073-08-7

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167073-08-7 Usage

Description

(1R,2S)-2-fluorocyclopropanecarboxylic acid is a cyclopropane derivative with the molecular formula C4H5FO2, featuring a fluorine atom and two chiral centers. The naturally occurring form is the (1R,2S) configuration, which possesses unique structural and electronic properties that make it a valuable compound in various chemical applications.

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
(1R,2S)-2-fluorocyclopropanecarboxylic acid is utilized as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and electronic properties contribute to the development of new and effective compounds with potential therapeutic and pesticidal activities.
Used in Organic Chemistry as a Building Block:
(1R,2S)-2-fluorocyclopropanecarboxylic acid serves as a versatile building block in organic chemistry for the preparation of more complex molecules. Its presence in the synthesis process can lead to the creation of novel compounds with diverse applications.
Used in Enhancing Chemical Reactivity and Biological Activity:
The fluorine substituent on the cyclopropane ring of (1R,2S)-2-fluorocyclopropanecarboxylic acid may impart specific chemical reactivity and biological activity to the compound. This feature can be exploited in the design of new molecules with improved properties, such as increased stability, selectivity, or potency in various applications across different industries.

Check Digit Verification of cas no

The CAS Registry Mumber 167073-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,7,0,7 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 167073-08:
(8*1)+(7*6)+(6*7)+(5*0)+(4*7)+(3*3)+(2*0)+(1*8)=137
137 % 10 = 7
So 167073-08-7 is a valid CAS Registry Number.
InChI:InChI=1S/C4H5FO2/c5-3-1-2(3)4(6)7/h2-3H,1H2,(H,6,7)/t2-,3-/m0/s1

167073-08-7Relevant articles and documents

Novel process for synthesizing 2 -fluorocyclopropylamine with high selectivity and asymmetric synthesis

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Paragraph 0070-0072, (2021/10/13)

A novel highly selective asymmetric synthesis process of 2 -fluorocyclopropylamine (Structural I). The method provided by the invention uses 1 - fluorine -1 - benzene (propylene) sulfonyl methane and chiral epichlorohydrin to construct chiral cyclopropane under basic conditions, and a new synthetic route not only achieves a special cis-trans selectivity, but also has a highly specific stereoselectivity. The synthesis route is efficient, the reaction condition is mild, the method is suitable for large industrial production in a green environment, 2 -fluorocyclopropylamine production cost is greatly reduced.

Racemic recovery method of by-product in resolution mother liquor of intermediate of sitafloxacin

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Paragraph 0040; 0041, (2019/01/07)

The invention discloses a racemic recovery method of the by-product in a resolution mother liquor of an intermediate of sitafloxacin. The method specifically comprises following steps: (1) carrying out resolution on a raceme 2-fluorocyclopropanecarboxylic

Stereoselective synthesis of cis -2-fluorocyclopropanecarboxylic acid

Shibue, Taku,Fukuda, Yasumichi

, p. 7226 - 7231 (2014/08/18)

A rhodium-catalyzed cyclopropanation of 1-fluoro-1-(phenylsulfonyl)ethylene and diazo esters is described as an effective method for the stereoselective synthesis of cis-2-fluorocyclopropanecarboxylic acid. This process provides an example of the cyclopro

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