16782-23-3Relevant articles and documents
Electrogeneration of the Anion of Ethyl Nitroacetate and Its Use in Electroorganic Synthesis
Niyazymbetov, Murat E.,Evans, Dennis H.
, p. 779 - 783 (1993)
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Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent
Li, Peng,Wu, Siqi,Xiao, Tianyichen,Li, Yunlong,Su, Zhiming,Wei, Wei,Hao, Fei,Hu, Guoping,Lin, Fusen,Chen, Xinsheng,Gu, Zhengxian,Lin, Tianwei,He, Haiying,Li, Jian,Chen, Shuhui
, (2020/05/18)
We describe here the design, synthesis, and evaluation of a macrocyclic peptidomimetic as a potent agent targeting enterovirus A71 (EV71). The compound has a 15-membered macrocyclic ring in a defined conformation. Yamaguchi esterification reaction was used to close the 15-membered macrocycle instead of the typical Ru-catalyzed ring-closing olefin metathesis reaction. The crystallographic characterization of the complex between this compound and its target, 3C protease from EV71, validated the design and paved the way for the generation of a new series of anti-EV71 agents.
One-pot multifunctional catalysis with NNN-Pincer Zr-MOF: Zr base catalyzed condensation with Rh-catalyzed hydrogenation
Rasero-Almansa, Antonia M.,Corma, Avelino,Iglesias, Marta,Sánchez, Félix
, p. 3092 - 3100 (2013/10/21)
We describe the postsynthetic modification of Zr-based metal organic frameworks (MOFs) containing chiral NNN-pincer ligands based on aminopyridineimines, as well as the subsequent formation of (NNN)-M-Zr-MOF complexes (M=Rh, Ir). With these new multifunct