168261-64-1

Basic information

• Product Name: (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)succinic acid 4-benzyl ester 1-tert-butyl ester
• Synonyms: (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)succinic acid 4-benzyl ester 1-tert-butyl ester
• CAS NO: 168261-64-1
• Molecular Weight: 501.579
• Mol File: 168261-64-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)succinic acid 4-benzyl ester 1-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)succinic acid 4-benzyl ester 1-tert-butyl ester(168261-64-1)
• EPA Substance Registry System: (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)succinic acid 4-benzyl ester 1-tert-butyl ester(168261-64-1)

Safety Data

• Hazardous Substances Data: 168261-64-1(Hazardous Substances Data)

Upstream product

• 129460-09-9 Fmoc-Asp-O-t-Bu 
• 100-39-0 benzyl bromide 
• 98946-18-0 tert-Butyl 2,2,2-trichloroacetimidate 
• 150009-58-8 9-fluorenylmethoxycarbonyl-O-benzyl-L-aspartic acid 
• 75-65-0 tert-butyl alcohol 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 94347-11-2 4-benzyl 1-t-butyl L-aspartate 

Downstream Products

• 94347-11-2 4-benzyl 1-t-butyl L-aspartate 
• 223480-02-2 methyl-6-O-carboxy-(N-(9-fluorenylmethoxycarbonyl)-L-aspartic-acid α-tert-butyl ester)-2,3,4-tri-O-4-methoxybenzyl-α-D-manno-pyranoside 
• 223480-00-0 methyl-6-O-carboxy-(N-(9-fluorenylmethoxycarbonyl)-L-aspartic-acid α-tert-butyl ester)-2,3,4-tri-O-benzyl-α-D-manno-pyranoside 
• 223480-06-6 ethyl-6-O-carboxy-(N-(9-fluorenylmethoxycarbonyl)-L-aspartic acid)-2,3,4-tri-O-benzyl-1-thio-α-D-manno-pyranoside 
• 129460-09-9 Fmoc-Asp-O-t-Bu 

Relevant articles and documents

Linker Variation and Structure-Activity Relationship Analyses of Carboxylic Acid-based Small Molecule STAT3 Inhibitors

The molecular determinants for the activities of the reported benzoic acid (SH4-54), salicylic acid (BP-1-102), and benzohydroxamic acid (SH5-07)-based STAT3 inhibitors were investigated to design optimized analogues. All three leads are based on an N-met

Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1

Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro. The Royal Society of Chemistry 2009.

A convenient preparation of several N-linked glycoamino acid building blocks for efficient solid-phase synthesis of glycopeptides

A high yielding route for the preparation of several Boc- and Fmoc-protected N-linked glycopeptide monomers was presented. It was found that these building blocks can be used for the solid-phase synthesis of glycopeptides or glycopeptidomimetics. A number of short glycopeptides- collagen mimics was prepared to demonstrate this applicability. The protocol employed was expected to be suitable for the synthesis of any desired N-linked glycopeptide.