16913-63-6

Usage

InChI:InChI=1/C9H10N2O2S2/c1-10(2)9(14)15-8-5-3-7(4-6-8)11(12)13/h3-6H,1-2H3

Upstream product

• 100-05-0 4-nitrobenzenediazonium chloride 
• 100-00-5 4-chlorobenzonitrile 
• 128-04-1 sodium dimethyldithiocarbamate 
• 137-26-8 Thiram 
• 24067-17-2 4-nitrophenylboronic acid 
• 75-15-0 carbon disulfide 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 124-40-3 dimethyl amine 
• 636-98-6 p-nitrobenzene iodide 

Downstream Products

• 21969-11-9 1-(4-chlorophenylthio)-4-nitrobenzene 

Relevant academic research and scientific papers

Aryldithiocarbamates as thiol alternatives in Cu-catalyzed C(aryl)-S coupling reactions using aryldiazonium tetrafluoroborate salts

An efficient method for the synthesis of unsymmetrical diaryl sulfides has been developed by the C-S cross coupling of aryldithiocarbamates and aryldiazonium salts in the presence of CuI-2,2′-bipyridine and Zn. Aryldithiocarbamate compounds have been used here as thiol substitutes. The protocol shows wide substrate scope and good yields of the products.

Copper-Catalyzed S-Arylation Starting from Arylboronic Acids and Tetraalkylthiuram Disulfide

A convenient and useful protocol for the synthesis of diverse S-aryl dithiocarbamates was studied. Starting from arylboronic acid and tetraalkylthiuram disulfide, copper-catalyzed C–S coupling proceeds smoothly to give the desired S-aryl dithiocarbamates in good to excellent yields. The broad substrate scope, short reaction time, easy performance, cheap substrates, and nice yields make this approach attractive, showing its practical synthetic value for the preparation of some biologically or pharmaceutically active compounds.

Copper-Catalyzed C(sp2)-S Coupling Reactions for the Synthesis of Aryl Dithiocarbamates with Thiuram Disulfide Reagents

An efficient protocol for the copper-catalyzed preparation of aryl dithiocarbamates from aryl iodides and inexpensive, environmentally benign tetraalkylthiuram disulfides was developed. The features of mild reaction conditions, high yields, and broad substrate scope render this new approach synthetically attractive for the preparation of potentially biologically active compounds.