17017-58-2

Basic information

• Product Name: 1-BENZYL-3-METHYL-1H-INDOLE
• Synonyms: 1-BENZYL-3-METHYL-1H-INDOLE
• CAS NO: 17017-58-2
• Molecular Formula: C₁₆H₁₅N
• Molecular Weight: 221.3
• Mol File: 17017-58-2.mol
• Article Data: 37

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BENZYL-3-METHYL-1H-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-3-METHYL-1H-INDOLE(17017-58-2)
• EPA Substance Registry System: 1-BENZYL-3-METHYL-1H-INDOLE(17017-58-2)

Safety Data

• Hazardous Substances Data: 17017-58-2(Hazardous Substances Data)

Upstream product

• 126920-19-2 N-benzyl-3-methyl-2,3-dihydro-1H-indole 
• 501346-53-8 1-benzyl-3-methyl-2,3-dihydro-1H-indol-3-ol 
• 133931-11-0 N-allyl-N-benzyl-2-bromoaniline 
• 83-34-1 3-Methylindole 
• 100-39-0 benzyl bromide 
• 15174-76-2 1-benzyl-3-methyl-5,6-dihydro-1H-indol-2(4H)-one 
• 36810-72-7 (N-benzyl-anilino)-acetone 
• 109-97-7 pyrrole 
• 10511-51-0 1-Benzylindole-3-carboxaldehyde 
• 34943-91-4 1-benzyl-3-methyl-1,3-dihydro-2H-indol-2-one 
• 34944-05-3 1-benzyl-3-hydroxy-3-methyl-2-oxo-2,3-dihydroxyindole 
• 91-56-5 indole-2,3-dione 
• 1217-89-6 1-benzylisatin 
• 120-72-9 indole 

Downstream Products

• 65-85-0 benzoic acid 
• 876337-60-9 carbonic acid 1-benzyl-3-methyl-1H-indol-2-yl ester phenyl ester 
• 1438392-99-4 (4aR,9aR)-9-benzyl-4a-methyl-3-phenyl-4,4a,9,9a-tetrahydro-[1,2]oxazino[6,5-b]indole 
• 1627942-14-6 3-(1-benzyl-3-methyl-1H-indol-2-yl)-4a,8a-dihydro-3H-quinazolin-4-one 
• 1627942-15-7 3-(1-benzyl-3-methyl-1H-indol-2-yl)-4a,10a-dihydro-3H-benzo[g]quinazolin-4-one 
• 1627942-16-8 3-(1-benzyl-3-methyl-1H-indol-2-yl)-3H-pyrimidin-4-one 
• 1644247-82-4 ethyl 2-(1-benzyl-3-methyl-1H-indol-2-yl)-2,2-difluoroacetate 
• 1616957-85-7 (N-benzyl-3,4-dimethyl-indol-2-yl)(3,5-dimethylphenyl)methanol 
• 1616957-37-9 C₃₄H₃₂N₂ 
• 1027804-34-7 1-benzyl-3-methyl-1H-indole-2-carbaldehyde 
• 1257268-92-0 1-benzyl-3-methyl-2-(trifluoromethyl)-1H-indole 
• 1609470-46-3 C₂₃H₁₉F₂NO₂S 
• 1592896-89-3 C₂₃H₂₅NO 

Relevant articles and documents

Palladium-catalysed intramolecular annulation of 2-haloanilines and ketones: Enolate arylation vs. nucleophilic addition to the carbonyl group

Two alternative annulation pathways involving either the enolate arylation or the addition to the ketone carbonyl group can operate in the Pd-catalysed intramolecular coupling of 2-haloanilines and ketones.

Solid-State Radical C?H Trifluoromethylation Reactions Using Ball Milling and Piezoelectric Materials

The application of piezoelectricity for the generation of trifluoromethyl (CF3) radicals is reported together with the development of a method for the mechanochemical C?H trifluoromethylation of aromatic compounds. As compared to conventional solution-based approaches, this mechanoredox C?H trifluoromethylation enables cleaner and more sustainable access to a wide range of trifluoromethylated N-heterocycles and peptides, which are important structural motifs in modern drug discovery. This study thus represents an important milestone for future applications of mechanoredox systems to medicinal and pharmaceutical science.

Room-Temperature Palladium(II)-Catalyzed Direct 2-Arylation of Indoles with Tetraarylstannanes

A palladium(II)-catalyzed direct 2-arylation of indoles by tetraarylstannanes with oxygen (balloon) as the oxidant at room temperature has been developed. Various tetraarylstannanes can be employed as aryl sources for 2-arylation of indoles in up to 89% yield, providing a practical and efficient catalytic protocol for accessing 2-arylindoles.