171734-48-8Relevant articles and documents
Enantioselective desymmetrization of prochiral ketones via an organocatalytic deprotonation process
Claraz, Aurelie,Oudeyer, Sylvain,Levacher, Vincent
, p. 764 - 768 (2013/07/25)
The first desymmetrization of 4-substituted cyclohexanones by organocatalytic asymmetric deprotonation at low catalyst loading is reported. The combination of N,O-bis(trimethylsilyl)acetamide (BSA) and chiral quaternary ammonium aryloxide salts has been u
Towards energetically viable asymmetric deprotonations: Selectivity at more elevated temperatures with C2-symmetric magnesium bisamides
Bennie, Linsey S.,Kerr, William J.,Middleditch, Michael,Watson, Allan J. B.
supporting information; experimental part, p. 2264 - 2266 (2011/04/12)
A novel chiral magnesium bisamide has enabled the development of effective asymmetric deprotonation protocols at substantially more elevated temperatures. This new, structurally simple, C2-symmetric magnesium complex displays excellent levels o
Enantioselective approaches to potential MetAP-2 reversible inhibitors
Rodeschini, Vincent,Van De Weghe, Pierre,Salomon, Emmanuel,Tarnus, Celine,Eustache, Jacques
, p. 2409 - 2412 (2007/10/03)
(Chemical Equation Presented) Enantioselective deprotonation of 4-substituted cyclohexanones and highly stereoselective conjugate addition of higher order mixed cuprates were the key steps in a concise synthesis of fumagalone-related molecules. The origin