1756-32-7Relevant articles and documents
Synthesis of asymmetrically substituted head-to-head polyacetylenes from 2,3-disubstituted-1,3-butadienes
Yu, Yunhai,Qu, Chengke,He, Junpo
, p. 395 - 402 (2019)
Asymmetrically substituted head-to-head polyacetylenes with phenyl and triphenylamine, thienyl or pyrenyl side groups were synthesized through anionic or controlled radical polymerization of 2,3-disubstituted-1,3-butadienes and subsequent dehydrogenation process. Anionic polymerizations of the designed monomers bearing pendent triphenylamine and thienyl group gave narrow disperse disubstituted precursor polybutadienes with exclusive 1,4- or 4,1-structure, which were confirmed by GPC and NMR measurements. In addition, the monomers possessing pyrenyl group were polymerized via nitroxide mediated radical polymerization and the resulting polymers were obtained with controlled molecular weight and low polydispersities. These polybutadiene precursors were then dehydrogenated in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone. Thus asymmetrically substituted head-to-head polyacetylenes were obtained as indicated by 1H NMR. The properties of polybutadiene precursors and the corresponding polyacetylenes were analyzed by UV–vis, DSC, and TGA.
Exhaustive hydrodefluorination of aryl trifluoromethyl ketones in a Zn-HOAc-DMF system
Moskalev,Zhuravkov,Ogorodnikov
, p. 2461 - 2461 (1996)
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High quantum yield both in solution and solid state based on cyclohexyl modified triphenylamine derivatives for picric acid detection
Zhang, Yuyang,Pan, Jianting,Zhang, Chenyang,Wang, Haowei,Zhang, Gaobin,Kong, Lin,Tian, Yupeng,Yang, Jiaxiang
, p. 257 - 266 (2015)
Five triphenylamine derivatives containing cyclohexyl have been designed and synthesized with a solvent-free green procedure. The compounds possess high quantum yields both in solution and solid state. Our investigation shows that the steric effects of th
Tuning of the excitation wavelength in Eu3+-aminophenyl based polyfluorinated β-diketonate complexes: a red-emitting Eu3+-complex encapsulated in a silica/polymer hybrid material excited by blue light
Usha Gangan,Reddy
, p. 15924 - 15937 (2015)
We describe herein the synthesis, characterization and photophysical properties of a series of europium complexes based on three aminophenyl based polyfluorinated β-diketonates, namely, 1-(4-aminophenyl)-4,4,5,5,5-pentafluoro-3-hydroxypent-2-en-1-one, 1-(
A Pd/Cu-Free magnetic cobalt catalyst for C-N cross coupling reactions: synthesis of abemaciclib and fedratinib
Hajipour, Abdol R.,Khorsandi, Zahra,Sarfjoo, Mohamad Reza,Varma, Rajender S.
supporting information, p. 5222 - 5229 (2021/07/29)
Herein, the synthesis of a nano-catalytic system comprising magnetic nanoparticles as the core and edible natural ligands bearing functional groups as supports for cobalt species is described. Subsequent to its characterization, the efficiency of the catalyst was investigated for C-N cross-coupling reactions using assorted derivatives of amines and aryl halides. This novel and easily accessible Pd- and Cu-free catalyst exhibited good catalytic activity in these reactions using γ-valerolactone (GVL) at room temperature; good recyclability bodes well for the future application of this strategy. The introduced catalytic system is attractive in view of the excellent efficiency in an array of coupling reactions and its versatility is illustrated in the synthesis of abemaciclib and fedratinib, which are FDA-approved new and significant anti-cancer medicinal compounds that are prepared under green reaction conditions.
DIPHENYLAMINO-METHYLENE MALONONITRILE BASED COMPOUNDS AS FLUORESCENCE PROBES
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Page/Page column 20, (2020/03/23)
The present invention provides compounds of formula (I) and formula (II): or a pharmaceutically acceptable salt or a stereoisomer thereof; wherein, ring A and ring B have the meanings given in the specification. The compounds of the present disclosure are useful as fluorescence probe in detecting tubulin in a sample and therefore useful for the diagnosis of tubulin and its associated diseases like cancer in a subject.
